ヒキガエルに投与した^<24>Naおよび^<42>Kの分布

概要

論文の詳細を見る
The present paper deals with the distribution of administered ^<24>Na and ^<42>K in various organs of the adult toad (Bufo vulgaris), weighing about 200gr. Labeled sodium chloride (190μc/ml) or labeled potassium chloride (20μc/ml) was intraperitoneally injected in the proportion of 1.5ml per 100gr. body weight. Eighteen hours after administration, each toad was dissected to get seven organs: eye, brain, skin, liver, pancreas, kidney (with adrenal) and muscle (M. gastrocnemius). The measurement of radioactivity was performed on the ashed samples derived from the fresh organs and the dehydrated ones which were prepared by means of histological procedures such as fixation by formalin (10%, 7 hours), dehydration by alcohol and clearing in xylol. All the data are presented in Tables I and II. 1)With regard to the distribution of administered isotopes, the radiosodium retention per unit fresh weight of organ decreased in the following order: skin, pancreas, eye, kidney, muscle, brain and liver, while the radiopotassium retention showed a gradient in the decreasing order: muscle, pancreas, liver, kidney, brain, skin and eye. 2)Based on the results mentioned above, the organs are compared with one another as shown in Table III. It will be clear that endodermal and mesodermal organs show a higher concentration of labeled potassium, while ectodermal ones such as eye, skin and brain rather show a lower retention. Such a significant relationship is not apparent with regard to labeled sodium. 3)As indicated in the third column of Tables I and II, a large amount of radiosodium and radiopotassium was lost during histological procedures, and subsequently, the dehydrated organ contained only 1-13 per cent of ^<24>Na or ^<42>K incorporated into its fresh organ.
社団法人日本動物学会の論文
1959-04-15

ヒキガエルに投与した^<24>Naおよび^<42>Kの分布

スポンサーリンク

概要

著者

関連論文

スポンサーリンク