DFPP,血漿交換が有効であった急性散在性脳脊髄炎(ADEM)の1例

概要

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A 28-year-old woman was admitted ot our hospital with complaints of high fever, headache and disturbance of consciousness WBC count and protein level in the liquor were increased. A brain MRI suggested demyelination around the procelia. She was finally diagnosed as having acute disseminated encephalomyelitis (ADEM) due to infection of the rubella. Although she had received steroid pulse therapy twice, she fell into a semicoma. We therefore peroformed plasma exchange and double-filtration plasmaphereisis (DFPP). After the first plasma exchange, metal status was improved. She was treated further, twice with plasma exchange and three times with DFPP. She gradulally became able to speak and move, and finally she could walk with the aid of a cane. These results indicate plasma exchange of DFPP might be an effective therapy for ADEM.
日本アフェレシス学会の論文
1999-02-28