重症筋無力症における術前アフェレシス療法(<特集>免疫性神経疾患とアフェレシス,新しい展望)

概要

論文の詳細を見る
Myasthenia gravis (MG) is a prototype of antibody-mediated autoimmune disease in which antibodies against the nicotinic acetvlcholine receptor (AChR) cause a reduction of junctional AChR, resulting in a defect of neuromuscular transmission. Nowadays, patients with MG are treated with cholinesterase inhibitors, immunosuppressive agents, plasmapheresis, and thymectomy. Plasmapheresis is usually used for treatment of myasthenic crisis, but is also useful in preoperative management. We here report a retrospective study of MG patients who received plasmapheresis before surgery.
日本アフェレシス学会の論文
2004-10-31