Endolymphatic Hydrops by Administration of Vasopressin in the Rat
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概要
- 論文の詳細を見る
The anti-diuretic hormone, vasopressin, has been shown to be important in regulating inner ear fluid. We report on the involvement between Meniere's disease and vasopressin. We designed an experiment to determine whether vasopressin directly affects the fluid level. We chronically infused this hormone in rats and examined them for morphological signs of endolymphatic hydrops. Vasopressin infusion significantly increased the scala media area by 5.9±7.1% (P<0.01), and the length of Reissner's membrane by 5.9±3.2% (P<0.001). The results suggest that high plasma levels of vasopressin may be a principal causal factor of endolymphatic hydrops in Meniere's disease, perhaps due to down-regulating the number of vasopressin receptors.
- 日本組織細胞化学会の論文
著者
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Takeda Setsuko
Department Of Otolaryngology Kouchi Medical School
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SUZUKI Mikio
Department of Molecular and Cell Genetics, School of Life Sciences, Faculty of Medicine, Tottori Uni
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KIMURA Hiroshi
Central Research Laboratory, Mitsubishi Electric Corporation
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Tooyama Ikuo
Central Research Laboratory And Molecular Neurobiology Research Center Shiga University Of Medical S
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Takeda Taizo
Department of Otolaryngology, Kochi Medical School
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Takeda Setsuko
Department Of Hepato-biliary-pancreatic Surgery Osaka City University Graduate School Of Medicine
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Kitano Hiroya
Department of Otolaryngology, Kouchi Medical School
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Kitanishi Tsuyoshi
Department of Otolaryngology, Kouchi Medical School
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Kitajima Kazutomo
Department of Otolaryngology, Kouchi Medical School
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Takeda Taizo
Department Of Otolaryngology Kouchi Medical School
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Kitano Hiroya
Department Of Otolaryngology Kouchi Medical School
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Kitajima Kazutomo
Department Of Otolaryngology Kouchi Medical School
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Kitano Hiroya
Department Of Otolaryngology Head And Neck Surgery Faculty Of Medicine Tottori University
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Kitanishi Tsuyoshi
Department Of Otolaryngology Kouchi Medical School
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Suzuki Mikio
Department Of Otolaryngology Kouchi Medical School
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Suzuki Mikio
Department Of Molecular And Cell Genetics School Of Life Sciences Faculty Of Medicine Tottori Univer
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Kimura Hiroshi
Central Research Laboratory And Molecular Neurobiology Research Center Shiga University Of Medical S
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Suzuki Mikio
Department of Applied Chemistry, Faculty of Technology, Gunma University
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