MYOGLOBIN IMMUNOHISTOCHEMICAL STUDIES ON RHABDOMYOLYSIS WITH ACUTE RENAL FAILURE
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概要
- 論文の詳細を見る
Immunohistochcmical localization of myoglobin (Mb) in muscles and kidneys was examined in three autopsy cases of rhabdomyolysis with acute renal failure. In the skeletal muscles, Mb immunoreactivity was lost in some degenerated fibers which was not expected by routine histological observations. In the kidneys Mb was revealed as fine granules in thc epithelial cells of the distal tubules, and as casts in collecting ducts. These findings confirmed that Mb leaked from myolytic fibers was partly reabsorbed, but mostly accumulated as Mb-casts in the collecting duct of the kidney, and caused an acute renal failure. Thus, Mb immunohistochemistry is helpful in identifying the direct process of acute renal failure caused by rhabdomyolysis.
- 日本組織細胞化学会の論文
著者
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Tanabe Hitoshi
Department Of Neurology Tokyo Metropolitan Neurological Hospital
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NAGASHIMA Toshiko
Departments of Neurology, Teine Keijinkai Hospital
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NAGASHIMA Kazuo
Second Department of Pathology, Hokkaido University School of Medicine
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Nagashima K
Laboratory Of Molecular And Cellular Pathology Hokkaido University Graduate School Of Medicine
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Nagashima T
Department Of Neurology Seiwa Memorial Hospital
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Nagashima Toshiko
Department Of Neurology Tokyo Metropolitan Neurological Hospital
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Nagashima Tadashi
National Research Institute Of Brewing:(present Address)technical Service Shin Nihon Chemical Co. Lt
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Nagashima Kazuo
Department Of Pathology Faculty Medicine Hokkaido University
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Nagashima T
Teikyo Univ. School Of Medicine Ichihara Hospital
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Nagashima Kazuo
Pathology Sapporo Higashi-tokushukai Hospital
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Nagashima Kazuo
Second Department Of Pathology Hokkaido University School Of Medicine
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