CHANGES IN GLYCOLYTIC ENZYME ACTIVITIES AND CYCLIC NUCLEOTIDE LEVELS OF CULTURED BOVINE VASCULAR CELLS IN HYPERLIPIDEMIC MEDIA (<Symposium>Histo- and Cytochemistry in Tissue Culture)
スポンサーリンク
概要
- 論文の詳細を見る
Comparative studies on changes in glycolytic and hydrolytic enzyme activities and cyclic nucleotide contents in bovine vascular smooth muscle cells were carried out in an attempt to elucidate the metabolic changes which occur in vascular cells, under condition of hyperlipidemia. Decreased glycolytic enzymes and increased acid phosphatase activities were found in smooth muscle cells cultured with 5% hyperlipidemic LDL which contained many sudanophilic droplets in their cytoplasma. Statistically significant low levels of cAMP and high levels of cGMP were confirmed in these cells cultured in hyperlipidemic media, as compared with those in control cells. This data suggests that decrease in cyclic AMP content and glycolytic enzyme activities accelerates lipid phagocytosis and cell division, both important phenomena in the course of atherosclerosis.
- 日本組織細胞化学会の論文
著者
-
Nishiyama Kenji
The Third Department Of Internal Medicine Tokyo Medical & Dental University
-
Nishiyama Keiji
The Cardiovascular Institute
-
SHIMOKADO KENTARO
Research Institute of the National Cardiovascular Center
-
NUMANO FUJIO
Department of Internal Medicine (3), Tokyo Medical and Dental University
-
Numano Fujie
The Their Department Of Internal Medicine Tokyo Medical And Dentao University
-
Numano Fujio
Department Of Cardiovascular Medicine Tokyo Medical And Dental University
-
Numano Fujio
Department Of Internal Medicne Tokyo Medical And Dental University.
-
Shimokado Kentaro
Department of Geriatrics and Vascular Medicine, Graduate School, Tokyo Medical and Dental University
-
Nishiyama Keiji
Department Of Anatomy Fukushima University School Of Medicine
-
Shimokado Kentaro
Department Of Geriatrics And Vascular Medicine Graduate School Of Medicine Tokyo Medical And Dental
-
Namba Ken-ichi
The Cardiovascular Institute
-
Nishiyama Keiji
Department Of Internal Medicne Tokyo Medical And Dental University.
-
Shimokado Kentaro
Department Of Internal Medicne Tokyo Medical And Dental University.
-
Numano Fujie
Department Of Internal Medicine (3) Tokyo Medical And Dental University
-
Shimokado Kentaro
Department Of Geriatric And Vascular Medicine Tokyo Medical And Dental University
-
Nishimura Kenji
The Cardiovascular Institute And Fukuda Denshi Co. Ltd
関連論文
- -P107- ASSESSMENT OF THE CHARACTERISTICS OF TRANSIENT COLLATERAL CIRCULATION DURING SUDDEN VASOSPASTIC CORONARY OCCLUSION
- PROGNOSIS OF VARIANT ANGINA WITH MEDICAL TREATMENT : Ischemic Heart Disease (I) : FREE COMMUNICATIONS (I) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Immunocytochemical Analysis of the AtheroscLerotic lesion : 54th Annual Scientific Session of the Japanese Circulation Society
- -0860-CELLULAR COMPOSITION OF THE REPARATIVE TISSUE RESPONSE AT THE SITES OF PTCA : AN IMMUNOCYTOCHEMICAL ANALYSIS USING MONOCLONAL ANTIBODIES : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Immunocytochemical analysis of the site of percutaneous transluminal coronary angioplasty (PTCA).
- Genetic Vulnerability of Cortical Neurons Isolated from Stroke-Prone Spontaneously Hypertensive Rats in Hypoxia and Oxygen Reperfusion
- CATECHOLAMINE RECEPTORS IN CULTURED BOVINE SMOOTH MUSCLE CELLS FROM CORONARY AND AORTIC TISSUES : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Myocardial Metabolism Biochemistry
- THE ROLE OF PROSTAGLANDINS ON THE PATHOPHYSIOLOGY OF VARIANT ANGINA : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Ischemic Heart Disease (II)
- Significance of methicillin-resistant Staphylococcus aureus (MRSA) survey in a university teaching hospital
- DOSE OF ASPIRIN AS ANTI-PLATELET DRUG : Surgery, Platelet and Thrombosis : FREE COMMUNICATIONS (III) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- High glucose concentrations impair the activation of K+ channels and proteases in undifferentiated THP-1 monocytes
- Visceral Leishmaniasis Misdiagnosed as Malignant Lymphoma
- PROGESTERONE TREATMENT OF TAKAYASU'S DISEASE : PROCEEDINGS OF THE 38TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- PULSED DOPPLER ECHOCARDIOGRAPHIC ASSESSMENT OF LV AND RV FILLING IN VASOSPASTIC ANGINA WITHOUT SIGNIFICANT CORONARY OBSTRUCTIVE LESIONS : Echocardiography (II) : FREE COMMUNICATIONS (IV) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE
- Peroxisome Proliferator-Activated Receptor α and γ Ligands Inhibit Expression ApolipoproteinB-48Receptor in Human monocytes and THP-1 Cells
- HLA-DR, MT AND MB ANTIGENS IN TAKAYASU DISEASE : Peripheral Circulation . Cerebral Circulation : 46th Annual Scientific Meeting, Japanese Circulation Society
- HLA and Clinical Manifestations in Takayasu Disease : SYMPOSIUM ON CLINICAL PROBLEMS IN AORTIC DISEASES
- CONSTITUTIONAL FACTORS IN TAKAYASU DISEASE : FROM THE STUDY OF MULTIPLEX FAMILIES WITH TAKAYASU DISEASE : Arrhythmia I, Immunity & Heredity, Contractile Protein : IVth Auditorium : Proceedings of the 43rd Annual Meeting of the Japanese Circulation Society
- TAKAYASU'S ARTERITIS. A FOLLOW-UP STUDY : Cardiomyopathy, Myocarditis : 53 Annual Scientific Meeting, Japanese Circulation Society
- -P254- CORONARY SMOOTH MUSCLE CELL DAMAGE BY ACTIVATED PLATELETS AND ITS PREVENTION
- BIOCHEMICAL STUDIES ON ALCOHOL INDUCED CORONARY SPASMS : Coronary Spasm : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- CHANGES IN GLYCOLYTIC ENZYME ACTIVITIES AND CYCLIC NUCLEOTIDE LEVELS OF CULTURED BOVINE VASCULAR CELLS IN HYPERLIPIDEMIC MEDIA (Histo- and Cytochemistry in Tissue Culture)
- CHANGES IN THE PLASMA LEVELS OF THROMBOXANE B_2 AND CYCLIC NUCLEOTIDES IN PATIENTS WITH TAKAYASU DISEASE
- PLASMA THROMBOXANE B_2 LEVELS IN TAKAYASU DISEASE : Coagulation, Arteriosclerosis : PROCEEDINGS OF THE 44th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- A Novel Contrast Medium Detects Increased Permeability of Rat Injured Carotid Arteries in Magnetic Resonance T2 Mapping Imaging
- Takayasu Arteritis
- HISTOENZYMATIC STUDY OF VESSEL WALL : Glycolytic enzyme activities in the arterial wall of man and various experimental animals and their changes at acute vascular injury or long term cholesterol feeding. : Proceedlngs of the 35th Annual Meetlng of the Ja
- Comparative Studies of Glycolytic Enzyme Activities in the Arterial wall of Man and Animals
- -170- ETIOLOGY OF AORTIC REGURGITATION IN TAKAYASU ARTERITIS : Myocardial Infarction, Valvular Heart Disease : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- CYCLIC NUCLEOTIDES RELEASE WITHIN THE CORONARY CIRCULATION RESPONSE TO ERGONOVINE MALEATE AND ISOSORBIDE DINITRATE : Coronary Circulation : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- CLINICAL SIGNIFICANCE OF PTCA IN PATIENTS WITH VASOSPASTIC ANGINA : PTCA, Thrombosis : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- PLASMA THROMBOXANE B_2, 6-KETO PGF_ AND CYCLIC NUCLEOTIDES LEVELS AS RELATED TO TREADMILL EXERCISE TEST IN PATIENTS WITH ISCHEMIC HEART DISEASE
- ARTERIOGRAPHIC FEATURES OF MYOCARDIAL INFARCTION AFTER ALCOHOL INGESTION : Ischemic Heart Disease (V) : V : 48 Annual Scientific Meeting, Japanese Circulation Society
- THE ANGIOGRAPHIC CHARACTERISTICS OF CORONARY SPASM : RELATION OF CORONARY SPASM TO SITES, SHAPES AND SEVERITY OF ORGANIC STENOSIS : Ischemic Heart Disease (V) : V : 48 Annual Scientific Meeting, Japanese Circulation Society
- QUANTITATIVE ASSESSMENT OF CINEANGIOGRAPHIC LEFT VENTRICULAR CONTRACTION WITH REGIONAL CURVATURE : Cardiac Function (III) : III : 48 Annual Scientific Meeting, Japanese Circulation Society
- INTRACORONARY PLATELET ACTIVATION DURING ERGONOVINE-INDUCED CORONARY SPASM : Ischemic Heart Disease (II), Coronary Circulation : II : 48 Annual Scientific Meeting, Japanese Circulation Society
- IDENTIFICATION OF MACROPHAGE-DERIVED CELLS IN ATHEROMATOUS LESIONS BY HYBRIDOMA MONOCLONAL MACROPHAGE ANTIBODY : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Pathology Morphology
- ECHOCARDIOGRAPHIC ANALYSIS OF PROPRANOLOL EFFECTS ON MYOCARDIAL CONTRACTILITY AND LEFT VENTRICULAR FUNCTION IN NORMALS AND PATIENTS WITH ISCHEMIC HEART DISEASE : Electrophysiology : 46th Annual Scientific Meeting, Japanese Circulation Society
- Histochemical Studies on ThromboxaneA_2-Induced Myocardial Infarction
- New Method of Estimating Myocardial Infarct Size Using Technetium-99m Pyrophosphate and Thallium-201 Dual Single Photon Emission Computed Tomography Imaging
- Long-Term Patency of an Aorta-Aortic Graft Bypass in a Patient with Takayasu Arteritis
- Platelet-Endothelium Interaction-A key Connection to Atherothrombotic Events
- P504 SENSITIVITY OF PLATELETS TO NITRIC OXIDE DECREASED AFTER EXERCISE IN NORMAL SUBJECTS
- 0779 PLATELETS ARE SUPERSENSITIVE TO NITRIC OXIDE AND PROSTACYCLIN IN ATHILETES
- -0817-EFFECTS OF ALCOHOL ON CYCLIC GMP METABOLISM IN CORONARY SMOOTH MUSCLE CELLS : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- -0609-ALTERATION OF ADENINE NUCLEOTIDE METABOLISM IN CORONARY SMOOTH MUSCLE CELLS BY ACTIVATED PLATELETS
- -213-SUPERSENSITIVITY OF PLATELETS TO LOWDOSE PROSTACYCLIN IN PATIENTS WITH ISCHEMIC HEART DISEASE : Ischemic Heart Disease I : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- CORONARY ARTERIOGRAPHIC STUDY OF ANGINA PECTORIS WITH ST-SEGMENT ELEVATION BEFORE AND AFTER ERGOMETER EXERCISE (III) : Ichemic Heart Disease (II) : 46th Annual Scientific Meeting, Japanese Circulation Society
- -0370-ASSESSMENT OF CORONARY ARTERY LESIONS OR MYOCARDIAL PERFUSION ABNORMALITIES IN PATIENTS WITH TAKAYASU'S ARTERITIS USING THALLIUM-201 SCINTIGRAPHY
- Coronary Sapsm, Prostaglandin and HLA Factors : SYMPOSIUM ON PATHOGENESIS OF CORONARY ARTERY SPASM
- A Smooth Muscle Cell Specific Monoclonal Antibody in the Immunocytochemical Analysis of Atherosclerotic Lesions
- Neuronal Damage of the Primary Afferent Neurons Elicits For Expression Even in the Spinal Dorsal Horn of the Capsaicin-induced Analgesic Rats
- PJ-528 Synergistic Effect of Atorvastaitn and Amlodipine in Stabilization of Acute Phase Leukocyte Recruitment to the Vascular Injury in Vivo(Infection/Inflammation/Immunity(03)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanes
- Evaluation of Peptidomimetic HTLV-I Protease Inhibitors Containing Hydroxymethylcarbonyl as a Transition-State Isostere
- EXPERIMENTAL STUDIES ON VEIN GRAFT ATHEROSCLEROSIS (I) HISTOCHEMICAL STUDIES USING MONOLONAL ANTIBODIES FOR SMOOTH MUSCLE CELLS AND MACROPHAGES
- Infiltration of β-Lipoprotein and Immunoglobulin-G into Aortic Wall of Rhesus Monkey (II)
- Microbiochemical Studies on Changes of Phosphofructokinase and Glucose-6-Phosphate Dehydrogenase Activity in Intima and Media of Aortic Wall of Rabbits in the Course of Cholesterol Feeding
- Histoenzymatic and Microbiochemical Analysis of Vessel Wall at Acute Vascular Changes
- Comparative Studies on Glycolytic Enzyme Activities in the Arterial Wall of Man : II
- COMPARATIVE STUDIES OF PATIENTS WITH TAKAYASU ARTERITIS IN JAPAN, KOREA AND INDIA : Comparison of Clinical Manifestations, Angiography and HLA-B Antigen
- CIRCULATING IMMUNE COMPLEXES IN TAKAYASU DISEASE
- FRS-028 Apollpoprotein CIII (apoCIII) Inhibits Insulin-dependent Endothelial Nitric Oxide Synthase (eNOS) Function in Endothelial Cells Through Protein Kinase C (PKC) βII(Novel Mechanisms in Atherosclerosis (IHD),Featured Research Session,The 72nd Annual
- Microbiochemical Analysis of Glycolytic Enzyme Activities in Human Arterial Wall : 1. Phosphofructokinase, Glucose-6-phosphate Dehydrogenase, Pyruvate Kinase and Hexokinase
- Histoenzymatic Analysis in the Aortic Wall of Rabbits at the Course of Cholesterol-Feeding and its Modefication by Estrogen or Pyridinol-carbamate Treatment
- PLASMA LEVELS OF THROMBOXANE B_2 AND CYCLIC NUCLEOTIDES DURING EXERCISE TEST IN PATIENTS OF ISCHEMIC HEART DISEASE : Ischemic heart disease : FREE COMMUNICATIONS (Abstract) : 45 Annual Scientific Meeting, Japanese Circulation Society
- Cholesterol Ester Hydrolase in Vessel Wall
- Histochemical and Biochemical Studies on Stress Ulcer in Water Immersion Restrained Rat
- Changes of cyclic nucleotides in the regressive course of experimental atherosclerosis and their modification by sex hormones and phthalazinol.
- OJ-175 Identification of the critical serine residues responsible for phosphorylation of endothelial E-selectin(Infection/Inflammation/Immunity 1 (H) : OJ20)(Oral Presentation (Japanese))
- OE-099 E-selectin-Triggered Recruitment of Endothelial Progenitor Cells to Vascular Endothelium is Significantly Enhanced by Preexisting Platelets(Molecular Biology, Vascular 1 (H) : OE12)(Oral Presentation (English))
- Suppressive effects of Neiting acupuncture on toothache: an experimental analysis on Fos expression evoked by tooth pulp stimulation in the trigeminal subnucleus pars caudalis and the periaqueductal gray of rats
- Inhibition of atresia leading to luteinization of ovarian preovulatory follicles by NS398, a specific cyclooxygenase-2 inhibitor
- SDF-1-triggered Adhesion of Human Monocytes to Vascular Endothelium is Modulated by Azelnidipine via Inhibition of Protein Kinase C Alpha (Atherosclerosis, Basic 9 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Glycogen in Endothelial Cells of Vessel Wall : Electron Microscopical Studies of Polyglucose Synthesized by Phosphorylase in Endothelial Cells of Aorta and Heart Muscles of Rabbits
- PE-324 Pitavastatin Inhibits Remnant Lipoprotein-induced Macrophage Foam Cell Formation via ApoB48 Receptor-dependent Mechanism(Atherosclerosis, Basic 5 (IHD) : PE55)(Poster Session (English))
- OJ-195 Sphingosine 1-phosphate induced monocyte-endothelial interaction involves PKC and RhoA dependent mechanism(Atherosclerosis, Basic 2 (IHD) : OJ22)(Oral Presentation (Japanese))
- PHOSPHODIESTERASE INHIBITORS: THEIR COMPARATIVE EFFECTIVENESS IN VITRO IN VARIOUS ORGANS
- Actions of the Japan Geriatric Society in response to the 2011 off the Pacific Coast of Tohoku Earthquake : First report
- Uric Acid Levels in Tissues and Plasma of Mice during Aging
- Ascorbic Acid Levels in Various Tissues, Plasma and Urine of Mice during Aging
- Effects of phthalazinol (EG 626) and pyridinolcarbamate (anginin) on lipolytic enzyme activities in rat adipose tissue -in vivo and in vitro-.
- CERVICAL SPINOUS PROCESS BIFURCATION IS NOT USEFUL AS A LANDMARK IN POSTERIOR CERVICAL SPINE APPROACH
- Left Ventricular Apical Aneurysm in Cardiac Sarcoidosis.
- Combination of amlodipine and atorvastatin synergistically reduces leukocyte recruitment to mechanically injured mouse femoral artery