IMMUNOCYTOCHEMICAL DEMONSTRATION OF _<α->FETOPROTEIN-POSITIVE CELLS IN THE LATE STAGE OF 3'-ME-DAB HEPATOCARCINOGENESIS
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概要
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We demonstrated _<α->fetoprotein (AFP)-positive cells in the late as well as in the early stage of 3'-methyl-4-dimethylaminoazobenzen (3'-Me-DAB) hepatocarcinogenesis, using immunocytochemical procedures with improved fixation and processing of tissue sections. The superior value of periodate-lysine-4% paraformaldehyde (PLP) as the fixative in the demonstration of AFP-positive cells and the usefulness of cryostat sections in floating immunoreactive processing are discussed. It is suggested that AFP-positive cells are new cell populations in the evolution of hepatocellular carcinoma.
- 日本組織細胞化学会の論文
著者
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Ibata Y
Kyoto Prefectural Univ. Medicine Kyoto Jpn
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Ibata Yasuhiko
Second Department Of Anatomy Kyoto Prefectural University Of Medicine
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IWAI Masaki
Third Department of Internal Medicine, Kyoto Prefectural University of Medicine
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Iwai Masaki
Third Department Of Internal Medicine Kyoto Prefectural University Of Medicine
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Iwai Masaki
Department Of Molecular Gastroenterology Hepatology Kyoto Prefectural University School Of Medical S
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Okuno Tadao
3rd Department Of Internal Medicine Kyoto Prefectural University
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Ibata Yasuhiko
Dept.of Anatomy And Neurobiology Kyoto Prefectural Univ.of Medicine
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TAKINO TATSURO
Third Department of Internal Medicine, Kyoto Prefectural University of Medicine
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Ishii M
Department Of Molecular Gastroenterology Hepatology Kyoto Prefectural University School Of Medical S
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Takino Tatsuro
3rd Department Of Internal Medicine Kyoto Prefectural University Of Medicine
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IBATA YASUHIKO
Third Department of Internal Medicine, Kyoto Prefectural University of Medicine
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OKUNO TADAO
Third Department of Internal Medicine Kyoto Prefectural University of Medicine
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Iwai Masaki
Third Department Of Internal Medicine And Kyoto Prefectural University Of Medicine
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