Persistence and Modulation of PTH/PTHrP Receptor Expression in Hypertrophic Cells of Mandibular Condylar Cartilage from Ovariectomized and Estrogen-treated Ovariectomized Adult Rats(Prof. K Watanabe Memorial Article)
スポンサーリンク
概要
- 論文の詳細を見る
The expression of parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) receptor in the mandibular condyles from sham-operated (Sham), ovariectomized (OVX), and OVX with 17β-estradiol (E_2)-treated (OVX+E_2) rats was investigated immunohistochemically with computer-aided image analysis. Western blot analysis for the receptor was also confirmed using these experimental cartilage models. The PTH/PTHrP receptor was preferentially localized in the hypertrophic chondrocytes throughout, and Western blot analysis revealed the protein expression in all of these cartilage models examined. Notably, OVX induced an enlargement of the hypertrophic chondrocytes, with larger indices of staining intensity and area as revealed by the image analysis; and E_2 treatment of OVX rats restored the values to nearly those of the Sham group. These findings suggest that the hypertrophic chondrocyte is a key regulatory site for the chondrocyte maturation and eventual matrix ossification in response to serum E_2 via the participation of PTH/PTHrP receptor in the adult rat mandibular condylar cartilage.
- 日本組織細胞化学会の論文
著者
-
KUSAMA Kaoru
Department of Pathology, Nihon University School of Dentistry
-
Kusama K
Department Of Oral Pathology Meikai University School Of Dentistry
-
Kusama Kaoru
Division Of Pathology Department Of Diagnostic And Therapeutic Sciences Meikai University School Of
-
Kusama Kaoru
Department Of Dental Pharmacology Meikai University School Of Dentistry
-
Kusama K
Division Of Pathology Department Of Diagnostic And Therapeutic Sciences Meikai University School Of
-
TAJIMA Yoshifumi
Department of Oral Pathology, School of Dentistry, Meikai University
-
Kuroda Mina
Department of Oral Pathology and, Meikai University School of Dentistry
-
Okazawa Jiroh
Department of Oral Pathology and, Meikai University School of Dentistry
-
Kurihara Kinji
Department of Oral Physiology, Meikai University School of Dentistry
-
Tajima Yoshifumi
Division Of Pathology Department Of Diagnostic And Therapeutic Sciences Meikai University School Of
-
Okazawa Jiroh
Division Of Pathology Department Of Diagnostic And Therapeutic Sciences Meikai University School Of
-
Tajima Yoshifumi
Department Of Oral Pathology Meikai University School Of Dentistry
-
Kuroda M
Department Of Oral Pathology And Meikai University School Of Dentistry
-
Kurihara Kinji
Department Of Oral Physiology Meikai University School Of Dentistry
関連論文
- 上顎残留嚢胞の術前検査にて判明したABO血液型亜型(B_m型)の1例
- 舌根部から顎下部にわたって認められた異所性甲状腺の1例
- エナメル上皮腫様組織を伴った歯牙腫の1例
- 9歳児の片側性に多発した下唇粘液嚢胞の1例
- Histopathological Reaction of a Calcium Phosphate Cement Root Canal Filler
- 疣贅型黄色腫29例の臨床的検討
- 唾液腺悪性腫瘍の増殖・進展メカニズムに関する研究 : cimetidine の及ぼす影響について
- 顎骨保存外科療法を施行した顎骨中心性粘液線維腫の1例
- 上唇に発生した粘液腺癌の1例
- 矯正治療を契機に認められたエナメル上皮腫の1例
- 大きな嚢胞様病態を呈した Warthin 腫瘍の1例
- 口底部MALTリンパ腫から生じたびまん性リンパ腫の1例
- 24年後の再発が認められた口蓋部唾液腺腫瘍の1例
- 顎下腺に発生した唾液腺管癌の1例
- 上顎前歯部に発症した歯原性線維腫の1例
- 多発性骨転移と高カルシウム血症をきたした上顎洞癌の1症例
- 耳下腺に発生した基底細胞腺腫の1例
- 下顎臼歯部に発生した良性セメント芽細胞腫の1例
- Eruption cyst with obvious epithelial hyperplasia in an infant
- Ameloblastic Fibro-odontoma Report of a Case and Review of the Japanese Literature
- A Case of Extensive Erythroplakia in the Oral Mucosa
- Keratocystic odontogenic tumor: a retrospective study of 183 cases
- Ameloblastic Fibroma : A critical evaluation of reported cases provides evidence of two types
- Papillary Cystadenoma of the Hard Palate : A case report
- α-Trifluoromethylacyloins Induce Apoptosis in HumanTumor Cell Lines
- Vascular Endothelial Growth Factor and Dendritic Cells in Squamous Cell Carcinoma of the Oral Cavity
- Dendritic Cells and Oral Cancer
- Polyphenols from Eriobotrya japonica and Their Cytotoxicity against Human Oral Tumor Cell Lines
- 舌に発生した結節性筋膜炎の1例
- Inflammatory Pseudotumor and Related Lesions of the Oral and Maxillofacial Region : A critical reappraisal based on recent infomation
- Trafficking of Green Fluorescent Protein-Tagged SNARE Proteins in HSY Cells
- Lipogranuloma arising in the collapsed mucous cyst of the lower lip following Castor oil application
- A case of rhizomegaly (radiculomegaly) of a primary tooth
- Persistence and Modulation of PTH/PTHrP Receptor Expression in Hypertrophic Cells of Mandibular Condylar Cartilage from Ovariectomized and Estrogen-treated Ovariectomized Adult Rats(Prof. K Watanabe Memorial Article)
- Elevated Maternal Serum Folate in the Third Trimester and Reduced Fetal Growth: A Longitudinal Study
- Ultrastructural demonstration of soybean agglutinin binding sites in mandibular condylar chondrocytes from normal, hypophysectomized, and growth hormone-treated hypophysectomized rats
- Parallel Distribution of Bcl-2 and Bax in Hypertrophied Chondrocytes of the Mandibular Condylar Cartilage from the Senescence-accelerated Mouse (SAMP3)
- ___- ___- effects of Tunicamycin on the mature chondrocytes of rat mandibular condyle as revealed by the lectin histochemistry
- WGA and Con A binding sites in the rat mandibular condylar cartilage as revealed by the lectin-gold complexes
- So-called Hybrid Odontogenic Tumors: Do they really exist?
- Ameloblastic fibrosarcoma arising de novo in the maxilla
- The use of silver enhancement technique for immunohistochemical demonstration of rat EGF
- Intravascular papillary endothelial hyperplasia of the oral cavity
- Light microscopic application of protein A-gold silver enhancement technique for immuno- and lectin histochemical examinations
- Podoplanin expression in odontomas: clinicopathological study and immunohistochemical analysis of 86 cases
- Molecular insights into the proliferation and progression mechanisms of the oral cancer : Strategies for the effective and personalized therapy
- Expression of heparanase: a possible role in invasiveness and aggressive clinical behavior of ameloblastomas
- Elevated Maternal Serum Folate in the Third Trimester and Reduced Fetal Growth : A Longitudinal Study
- Podoplanin promotes cell migration via the EGF-Src-Cas pathway in oral squamous cell carcinoma cell lines
- Immunohistochemical expression of podoplanin in so-called hard α-keratin-expressing tumors, including calcifying cystic odontogenic tumor, craniopharyngioma, and pilomatrixoma
- Activation-induced cytidine deaminase mRNA expression in oral squamous cell carcinoma-derived cell lines is upregulated by inflammatory cytokines
- The significance of podoplanin expression in human inflamed gingiva
- Expression of activation-induced cytidine deaminase in oral epithelial dysplasia and oral squamous cell carcinoma