膀胱腫瘍に対する温水療法の研究(第2報)

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Preliminary clinical studies suggested that hyperthermic treatment resulted in regression of bladder tumor. The present paper is aimed to discuss the efficacy of this method by analysing 69 cases of bladder tumors. The bladder was treated with heated irrigant 10 times continuously unless side effect occurred. Thio-Tepa or Adriamycin was added to the irrigant in some cases. 1) Complete and partial regressions were noted in 15 of the 69 cases and 28 of the 69 cases respectively, while no regression was observed in 26 of the 69 cases. Therefore, 63 per cent (43 of 69 cases) showed tumor regression by the hyperthermic treatment. In relation to the clinicopathological study and hyperthermia, regression was noted in 82 per cent of pedunculated tumors, 92 per cent of small tumors, 80 per cent of TI tumors, and 77 per cent of grade l tumors. 2) 18 cases with severe complication were treated with hyperthermia. Regression was seen in 56 per cent (10 of 18). 3 died of tumor and 2 died of cardiovascular diseases. 5 were alive over one year. 3) Intractable hematuria was terminated or controlled in 50 per cent (8 of 16) and macroscopic hematuria was terminated in 70 per cent (l9 of 27) following hyperthermia. 4) As the side effect, pronounced high blood pressure was recorded in 37 cases during the treatment. Following hyperthermia, acute epididymitis was found in 7 cases. 11 developed vesicoureteral reflux after the treatment.
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膀胱腫瘍に対する温水療法の研究(第2報)

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