日本人とネパール王国テチョー村住民の Phenyl-thio-carbamide (PTC) に対する味覚反応の比較

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The comparative PTC taste sensitivity of Japanese and Nepali people was investigated in 1990. This investigation was carried out by the paper method and the mouth rinse method. Nepali tasters were resident farmers of Thecho Village in Kathmandu valley. The total number of tasters was 401. The proportion of male to female was 241 males and 160 females. On the other hand, Japanese tasters consisted of 218 students, from 19 to 24 years old. The male-female proportion among Japanese students was 106 males and 112 females. The taste sensitivity of tasters examined by the paper method was distinguished as bitter tasters, nontasters and others. In this case, nontasters were classified as PTC nontasters, and bitter tasters and others were classified as PTC tasters. Nontasters shown by the paper method were treated by 5 ml of 1/120 M of PTC solution. After this treatment, the taste sensitivity of tasters were examined. According to the same concentration of PTC in the both methods, the tasters who answered 'no taste' were classified as PTC nontasters and who answered 'can taste' were classified as PTC tasters. 1. The rate of PTC nontasters between Japanese and Nepalis was compared by using with the paper method and mouth rinse method. The response to the mouth rinse method was lower than to the paper method among both nationalities. From these results, it may be recommended that the mouth rinse method should be carried out along the paper method when doing anthropological investigations. 2. The PTC blindness test was carried out on 218 Japanese students and 401 Nepalis. PTC nontasters among Japanese examined by the paper method were 16.1% and their male-female proportion was 17.9% for males and 14.3% for females. Japanese PTC nontasters by the mouth rinse method were 10.1% and their male-female proportion was 13.2% for males and 7.1% for females. In case of Nepalis, PTC nontasters by the paper method were 14.7% and their male-female proportion was 14.5% for males and 15.0% for females. On the other hand, Nepali PTC nontasters by the mouth rinse method were 6.7% and their male-female proportion was 7.1% for males and 6.3% for females. This comparison between both methods of the PTC nontasters rate of Japanese and Nepalis showed that there was no significant difference between the two methods. From this investigation and previous papers related to this field, the people of Thecho village seem to be more closely related to the Tibet-Mongolians race than to the India-Aryan race.
九州歯科学会の論文
1993-06-25

日本人とネパール王国テチョー村住民の Phenyl-thio-carbamide (PTC) に対する味覚反応の比較

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