A Case Report of Metastatic Carcinoma of the Gingiva

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概要

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• A 67-year-old male was admitted to the Clinic of Oral and Maxillofacial Surgery II, Dental Hospital, Matsumoto Dental University, with a chief complaint of a painless swelling of the mandibular gingiva. Under a clinical diagnosis of an epulis of the gingiva, surgical excision was performed. The material was then diagnosed histopathologically as a poorly differentiated carcinoma. After reporting the biopsy results, we obtained important information that the patient had been tentatively diagnosed as having hepatocellular carcinoma by clinical examination. Therefore, the tumor was further examined immunohistochemically. The immunohistochemical examination used some useful markers for the diagnosis of hepatocellular carcinoma, i.e., CEA, EMA, cz-1-ACT, cz-1-AT, albumin, ALP, and CK 7, 8, 18, 19. The examination results were positive for many immunohistochemical profiles of hepatocellular carcinoma, although there was no so-called "hepatoid pattern" in the histopathological observation. Finally the gingival carcinoma was considered to be a poorly differentiated metastatic carcinoma that had originated from a "hepatocellular carcinoma", as judged from our histopathological and immunohistochemical examinations. This was determined although the histopathological observation of the primary lesion in the liver was not carried out. No additional treatment was undertaken as according to the wishes of the family.

• 特定非営利活動法人日本臨床口腔病理学会の論文

著者

• Kawakami Toshiyuki

  Department of Hard Tissue Research, Matsumoto Dental University Graduate School of Oral Medicine

• Kawakami Toshiyuki

  Department Of Oral Pathology Matsumoto Dental University

• Kimura A

  松本歯科大学 口腔病理

• HASEGAWA Hiromasa

  Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine

• Kimura Akihiro

  Department of Medical Engineering and Systems Cardiology, Kawasaki Medical School

• Kawakami T

  松本歯科大学 口腔病理

• Hasegawa Hiromasa

  Department Of Cardiology Pulmonology And Nephrology Yamagata University School Of Medicine

• Eda Shigeo

  Department of Oral Pathology, Matsumoto Dental University

• Eda Shigeo

  Department Of Oral Pathology Matsumoto Dental University

• Kimura Akihiro

  Department Of Geriatric Medicine Tokyo Medical University

• Kawai Tatsushi

  Department Of Dental Material Science Aichi-gakuin University School Of Dentistry

• Eda Shigeo

  Department Of Oral Pathology Matsumoto Dental College

• Hasegawa Hiromasa

  Department of Oral pathology, Matsumoto Dental University

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