Pseudomonas属菌の色素代謝に関する研究(第1報) : Pseudomonas aeruginosaの生産する新黄色色素Pyoluteorinの単離およびその性質

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Two of the pyocyanogenic strains, T 359 and IFO 3455,when grown at 28℃ on beefextract broth containing CaCl_2 by shaking method, give rise to hitherto undescribed, chlorine-containing yellow fine needles, C_11H_7Cl_2NO_2,(m.p. 174〜175℃, decomp.), to which the name "Pyoluteorin" is proposed.Methods of isolation and antimicrobial activities of the substance are described. An ethanolic solution of the pigment shows an absorption maximum at 310 mμ, and chemical tests indicate that the substance has an aromatic nucleus containing chlorine and nitrogen.Pyoluteorin inhibits the growth of a number of bacteria including M. tuberculosis hominis and protozoa, but shows low activity against various fungi and yeasts.
公益社団法人日本生物工学会の論文
1958-07-15