ブタノール抽出発酵における抽剤の発酵阻害の回避

概要

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Organic solvents having relatively high distribution coefficients for butanol against water were often found to occur in higher alcohols, esters and organic acids; however, they were very toxic to the microorganisms for butanol fermentation. It was found that most of the fermentation inhibition caused by the solvent toxicity could be eliminated by re-extracting the solvent from the residual phase, to be recycled from the product extraction column to the fermenter by n-paraffin as an exractive fermentation process applied externally to the product extraction (Fig.1). After selectng 2-octanol as the extractant for the extractive fermentation from the standpoint of energy consumption in butanol recovery, a two-stage-extraction butanol extractive fermentation process having the possibility of reducing the production cost of butanol is proposed (Fig. 4).
社団法人日本生物工学会の論文
1992-07-25