ミニ移植およびImatinib Mesylateが一時的に有効であった化学療法不応性フィラデルフィア染色体陽性急性リンパ性白血病の1症例

概要

論文の詳細を見る
Mini-transplant was performed in a patient with Philadelphia chromosome (Ph1) positive acute lymphoblastic leukemia (ALL) which had been refractory to repeated courses of chemotherapy. Decrease of leukemic cells and mixed chimerism were observed during a first month. However, leukemic cells increased thereafter, and donor leukocyte infusion(DLI) was ineffective. Subsequently, Imatinib Mesylate was administered and leukemic cells decreased for 2 months, however lekemic cells increased thereafter. These treatments were temporarily effective for Ph1 positive ALL which was refractory to conventional chemotherapy. The improvement of these treatment strategies and accumulation of these cases are necessary.
山口大学医学会の論文
2002-12-31