^1H-MRS法による下腿筋群の中性脂肪含有量と体組成および有酸素能力との関係

概要

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The main purpose of this study was to evaluate intramyocellular (IMCL-TG) and extramyocellular triglyceride (EMCL-TG) contents of lower leg muscles by using proton magnetic resonance spectroscopy (^1H-MRS) and to analyze their relation to body composition and aerobic capacity. Eighteen young healthy male subjects engaged in varying degrees of physical activity participated in this study. The average IMCL-TG content of the tibialis anterior (TA), medial gastrocnemius (MG) and soleus (SOL) was 2.05±0.2, 4.76±0.5 and 7.41±0.4 (mean ± SE) mmol・kg^<-1> wet wt, respectively, and significant differences were found between the muscles (p<0.01). The EMCL-TG content of TA (0.89±0.1 ml・kg^<-1>・min^<-1>) was lower than that of MG (8.06±1.1 mmol・kg^<-1> wet wt) and SOL (5.99±0.6mmol・kg^<-1> wet wt). The IMCL-TG values of TA and MG were negatively correlated with body fat (r=-0.606 and r=-0.645 for TA, and MG, respectively ; p<0.01) and positively correlated with VO_2max (r=0639 and r=0.709 for TA, and MG, respectively ; p<0.01), but there were no correlations in EMCL-TG contents of each muscle for the body fat and VO_2max measurements. These results suggest that IMCL-TG content, as assessed non-invasively by ^1H-MRS, may reflect muscle metabolic characteristics, and also VO_2max as aerobic capacity.
日本運動生理学会の論文
2004-04-15