Identification of Basic Fibroblast Growth Factor-like Immunoreactivity in Panax ginseng Extract: Investigation of Its Molecular Properties
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概要
- 論文の詳細を見る
Basic fibroblast growth factor (bFGF)-like immunoreactivity was detected in extracts of Panax ginseng root by using a sensitive two-site enzyme immunoassay specific for human bFGF (hbFGF). In an investigation of the molecular properties of this bFGF-like molecule (bFGF-LI), the bFGF-LI and hbFGF were found to be equivalent with respect to antigenicity, molecular weight, isoelectric point, affinity for binding to heparin, and mitogenic activity toward BALB/c3T3 fibroblasts. The identification of this bFGF-LI molecule in Panax ginseng root helps to explain various activities of the traditional Chinese medicine ginseng.
- 社団法人日本農芸化学会の論文
- 1996-04-23
著者
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TAKEI Yoshifumi
Department of Biochemistry, Graduate School of Medicine, Nagoya University
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HAYASHI KYOZO
Department of Biology, Gifu Pharmaceutical University
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YAMAMOTO Toshiya
Department of Specific Organ Regulation, Division of Obstetrics and Gynecology, Osaka University Gra
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Hayashi Kyozo
Department Of Biochemistry Osaka University Of Pharmaceutical Sciences
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Yamamoto Toshiya
Department Of Breeding National Institute Of Fruit Tree Science
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Higashira Hanae
Department Of Molecular Biology Gifu Pharmaceutical University
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Takei Yoshifumi
Department Of Biochemisry Nagoya University School Of Medicine
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Takei Yoshifumi
Department Of Molecular Biology Gifu Pharmaceutical University
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Yamamoto Toshiya
Department Of Molecular Biology Gifu Pharmaceutical University
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