Effects of Homoserine Dehydrogenase Deficiency on Production of Cytidine by Mutants of Bacillus subtilis
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概要
- 論文の詳細を見る
A homoserine-requiring mutant, Bacillus subtilis strain No. 615, was isolated from a cytidine-producing mutant strain No. 515. The homoserine dehydrogenase activity of strain No. 615 was reduced to less than 1/50 of that of No. 515. Strain No. 615 accumulated 23.5 mg/ml cytidine in a medium containing 16% glucose, and strain No. 515 accumulated 18.8 mg/ml cytidine under the same conditions. The effects of glucose concentration on cytidine production were examined, and strain No. 615 accumulated 30.2mg/ml cytidine in a medium containing 20% glucose.
- 社団法人日本農芸化学会の論文
- 1996-02-23
著者
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Asahi Satoru
Fermentation Center Technology Development Laboratories Takeda Chemical Industries Ltd.
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Tsunemi Yutaka
Fermentation Center, Technology Development Laboratories, Takeda Chemical Industries, Ltd.
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Doi Muneharu
Fermentation Center Technology Development Laboratories Takeda Chemical Industries Ltd.
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Tsunemi Yutaka
Fermentation Center Technology Development Laboratories Takeda Chemical Industries Ltd.
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Akiyama S
Fermentation Center Technology Development Laboratories Takeda Chemical Industries Ltd.
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- Hyperproduction of Orotic Acid and Orotidine by Mutants of Bacillus subtilis
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