Practical Total Synthesis of (2S,3S,4R)-1-O-(α-D-Galactopyranosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol, the Antitumorial and Immunostimulatory α-Galactosylcer-amide, KRN7000
スポンサーリンク
概要
- 論文の詳細を見る
A practical total synthesis of (2S,3S,4R)-1-O-(α-D-galactopyranosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol (KRN7000), an antitumorial and immunostimulatory glycosphingolipid derived from agelasphins, was achieved in 14 steps starting from D-lyxose in a 16% overall yield.
- 社団法人日本農芸化学会の論文
- 1996-02-23
著者
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Sawa Eiji
Pharmacological Research Laboratories, Research Division, Kyowa Hakko Kirin Co., Ltd., Japan
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Sawa Eiji
Pharmaceutical Research Laboratory Kirin Brewery Co. Ltd.
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Fukushima Hideo
Department Of Biological And Chemical Engineering Faculty Of Engineering Gunma University
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SAKAI Teruyuki
Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd.
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MORITA Masahiro
Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd.
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YAMAJI Kazuo
Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd.
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NATORI Takenori
Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd.
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KOEZUKA Yasuhiko
Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd.
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FUKUSHIMA Hideaki
Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd.
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AKIMOTO Kohji
Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd.
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Yamaji Kazuo
Pharmaceutical Research Laboratory Kirin Brewery Co. Ltd.
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Morita M
Japan Women's Univ. Tokyo Jpn
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Akimoto Kohji
Pharmaceutical Research Laboratory Kirin Brewery Co. Ltd.
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Sakai Teruyuki
Pharmaceutical Research Laboratory Kirin Brewery Co. Ltd.
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Sakai Teruyuki
Pharmaceutical Research Laboratory
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Natori Takenori
Pharmaceutical Research Laboratory Kirin Brewery Co. Ltd.
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Fukushima Hideaki
Pharmaceutical Research Laboratory Kirin Brewery Co. Ltd.
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Koezuka Y
Kirin Brewery Co. Gunma Jpn
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Koezuka Yasuhiko
Pharmaceutical Research Laboratory Kirin Brewery Co
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