Endothelium-Derived Hyperpolarizing Factor (EDHF) : ROLES OF VASCULAR ENDOTHELIUM IN REGULATION OF CARDIOVASCULAR SYSTEM
スポンサーリンク
概要
- 論文の詳細を見る
In vascular tissues, many types of stimulants which release endothelium-derived relaxing factor (EDRF) hyperpolarized the smooth muscle membrane in an endothelium-dependent manner. The hyperpolarizations were resistant to inhibitors of the actions of EDRF, thereby suggesting that they were elicited by an unidentified substance called endothelium-derived hyperpolarizing factor (EDHF). The EDHF induced hyperpolarization was produced by an increase in K^+-permeability of the membrane, and was one of the factors to induce endothelium-dependent vasodilations. Release of EDHF required an increase in endothelial Ca<2+> , due eithr to release of Ca<2+> from intracellular storage or to its influx from the external media.
- 社団法人日本循環器学会の論文
- 1992-02-20
著者
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Yokoyama Y
Department Of Physiology Nagoya City University School Of Nursing
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Yokoyama Yoshifumi
First Department Of Internal Medicine Nagoya City University School Of Medicine
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YAMAMOTO Yoshimichi
Department of Physiology, Nagoya City University School of Nursing
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SUZUKI Hikaru
Department of Physiology, Nagoya City University Medical School
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Yokoyama Yoshifumi
The First Department Of Internal Medicine Nagoya City University Medical School
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Suzuki Hikaru
Department Of Physiology Nagoya City University Medical School
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Suzuki Hikaru
Department Of Cell Physiology Nagoya City University Medical School
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Yamamoto Y
Department Of Physiology Nagoya City University Nursing School
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Yamamoto Yoshimichi
Department Of Civil Engineering
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CHEN GUIFA
Department of Physiology, Nagoya City University Medical School
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Chen Guifa
Department Of Physiology Nagoya City University Medical School
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Yamamoto Yoshimichi
Lab. Of Physiology Nagoya City Univ. School Of Nursing
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Suzuki Hikaru
Department Of Cardiology Tokyo Women's Medical University
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Chen Guifa
Department of Pharmacology, Faculty of Medicine, Kyushu University
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