Relative Usefulness of Measures of Heart Rate Variability and Neuroendocrine Activity as Indicators of Autonomic Nervous Abnormality in Patients With Left Ventricular Dysfunction
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概要
- 論文の詳細を見る
The aim of the study was to assess the relationship between changes in heart rate variability(HRV)and parameters of neuroendocrine activation in patients with various leveles of left ventricular dysfunction.Measurements of HRV, plasma norepinephrine(PNE), and plasma atrial natriuretic peptide(ANP)were performed in 17 age- and gender-matched control subjects(group C)and in 39 patients with ischemic heart disease or cardiomyopathy who were subdivided into 3 equal groups according to their left ventricular ejection fraction:group N(normal);group M(mildly impaired);and group S(severely impaired).Spectral analysis of HRV(from 10-min electrocardiograms)was analyzed by the method of coarse-graining spectral analysis.PNE and ANP were significantly elevated in group S only(p<0.05).Log low-frequency power and log total power for group M were significantly lower than for group N(p<0.05).Log high-frequency power was significantly lower for group M than for group C(p<0.05).Thus, assessment of changes in HRV, which were observed earlier in the progress of left ventricular dysfunction than changes in neuroendocrine factors, may be a useful non-invasive method for the early detection of autonomic abnormality in patients with left ventricular dysfunction.
- 社団法人日本循環器学会の論文
- 1998-04-20
著者
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Yamamoto Takeshi
Department Of Medicine And Clinical Science Division Of Cardiology Yamaguchi University Graduate Sch
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Shimizu Akihiko
Faculty Of Health Sciences Yamaguchi University School Of Medicine
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Shimizu Akihiko
Second Department Of Internal Medicine Yamaguchi University
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Matsuzaki Masunori
Second Department of Internal Medicine, Yamaguchi University, School of Medicine
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Shimizu Akihiko
Division Of Cardiovascular Medicine Department Of Medical Bioregulation Yamaguchi University School
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Shiigi Toshiaki
Second Department of Internal Medicine, Yamaguchi University School of Medicine
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Furutani Yuhji
Second Department of Internal Medicine, Yamaguchi University School of Medicine
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Nakamura Yasuma
Second Department of Internal Medicine, Yamaguchi University School of Medicine
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Nakamura Hiroshi
Second Department of Internal Medicine, Yamaguchi University School of Medicine
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Harada Masahiko
Second Department of Internal Medicine, Yamaguchi University School of Medicine
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Yamamoto Takeshi
Second Department of Internal Medicine, Yamaguchi University School of Medicine
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Furutani Yuhji
Second Department Of Internal Medicine Yamaguchi University School Of Medicine:national Hamada Hospi
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Nakamura Yasuma
Division Of Cardovascular Medicine Department Of Medical Bioregulation Yamaguchi University Graduate
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Nakamura Yasuma
Second Department Of Internal Medicine Yamaguchi University School Of Medicine
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Shiigi Toshiaki
Yamaguchi University
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Shimizu Akihiko
Department Of Nursing Yamaguchi University School Of Medicine
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Takahashi Yojiro
Division Of Cardiovascular Medicine Department Of Medical Bioregulation Yamaguchi University School
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Matsuzaki Masunori
Second Department Of Internal Medicine Yamaguchi University School Of Medicine
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Furutani Yuuji
Second Department Of Internal Medicine Yamaguchi University School Of Medicine
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Furutani Yuhji
The Second Department Of Internal Medicine University Of Yamaguchi Ube And Yamato Hospital
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Harada Masahiko
Division Of Cardiovascular Medicine Department Of Medical Bioregulation Yamaguchi University School
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Harada Masahiko
Second Department Of Internal Medicine Yamaguchi University School Of Mediciney
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Shiigi Toshiaki
Second Department Of Internal Medicine Yamaguchi University School Of Medicine
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Furutani Yuhji
Second Department Of Internal Medicine Yamaguchi University School Of Medicine
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Nakamura Yasuma
The Second Division Department Of Internal Medicine Yamaguchi University School Of Medbine
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Shimizu Akihiko
Department Of Cardiovascular Medicine Yamaguchi University Graduate School Of Medicine
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Mori Masaki
Division Of Gene Therapy Science Osaka University
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Yamamoto Takeshi
Division Of Cardiovascular Medicine Department Of Medical Bioregulation Yamaguchi University School
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Furutani Yuhji
Second Department Of Internal Medicine Yamaguchi University
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Shimizu Akihiko
Faculty Of Health Sience Yamaguchi University Graduated School Of Medicine
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Takahashi Yojiro
The Second Division Of Internal Medicine Yamaguchi University School Of Medicine
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Yamamoto Takeshi
Division Of Cardiology Tokuyama Central Hospital
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