小児期における真菌過敏喘息の臨床的研究

概要

論文の詳細を見る
This report is given of the results of skin tests, inhalation tests and specific hyposensitization therapy with five species of Torii mold extracts (Aspergillus, Alternaria, Cladosporium, Candida, Penicillium) on infants and children with bronchial asthma who visited our clinic. The results were as follows: 1. Seventeen (16.2%) of 105 patients reacted positively to scratch tests with extracts of five species of molds. 2. Two hundred ninety (50.2%) of 578 patients reacted positively to intracutaneous tests with molds. 3. Inhalation tests were made on 168 patients who were skin sensitive to mold, and 73 (43.5%) of these displayed positive provocative reactions to one or more of the five mold extracts. Alternaria and Candida gave rise to positive provocative reactions rather more frequently than did the other extracts. 4. From the observation above, it can be assumed that about 20 per cent of asthmatic children are sensitive to molds. 5. The rate of positive reactors to inhalation tests with mold extracts showed a tendency to decrease with the advance in age. 6. Most mold-sensitive patients gave a history of aggravation of symptoms in autumn but slight difference was recognized as to seasonal aggravation among the different species of molds. 7. According to the results of inhalation tests with house dust and molds on the same subject, relatively many patients reacted positively to either house dust or mold extracts but only 26.5 per cent were sensitive to both. 8. Twenty-nine patients who were sensitive to molds were treated over one year period with various mold extracts. Consequently 65.5 per cent of these showed a remarkable improvement in symptoms. The incidence of side effects resulting from hyposensitization therapy was 17.1 per cent.
日本アレルギー学会の論文
1970-02-28

小児期における真菌過敏喘息の臨床的研究

スポンサーリンク

概要

著者

関連論文

スポンサーリンク