Application of a Newly Developed Photoluminescence Glass Dosimeter for Measuring the Absorbed Dose in Individual Mice Exposed to Low-dose Rate ^^137 Cs γ-rays

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A photoluminescence glass dosimeter, GD-301, was applied to the measurement of low absorbed doses in mice exposed to low-dose rate ^<137>Cs γ-rays. The dosimeter system consists of small rod-shaped glass chip detectors capable of embedded in the body of a mouse and an automatic readout device equipped with a standard detector irradiated with ^<137>Cs γ-source. The measured absorbed doses were compared with the "exposure" estimated by an ionization chamber and with the doses measured by a BeO:Na thermoluminescence system. The results clearly demonstrate the superiority of the glass dosimetry regarding simplicity of operation, stability of long-term dose accumulation and good detector uniformity, which allow accurate tissue dosimetry. INTRODUCTION Direct measurements of absorbed doses in small experimental animals, such as mice, have been commonly performed using a thermoluminescent dosimeter (TLD)1,2), since its small size enables it to be embedded in the mouse body, for instance, in the peritoneal cavity. However, TLD system, at least the version commonly available for general radiobiological experiments, has a limitation especially in measuring low dose, due to a lack of detector uniformity, and a significant pre-dose inherent to surface contamination3).
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