RBE of HTO to ^<60>Co Gamma-Rays for Cell Killing of A Radioresistant E. coli Harboring Plasmid
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Radioresistant E. coli TGI harboring pUC 18 plasmid which was Ampicillin-resistant was exposed to ^<60>Co gamma-rays or ^3H beta-rays in saline to determine whether the relative biological effectiveness of ^3H beta-rays is higher than one. After exposure to ^<60>Co gamma-rays at a dose rate of 0.465 Gy/min, the Do by colony formation was 145 Gy in the presence of Ampicillin in or absence from the agar medium; whereas, the D_0 was calculated as 118 Gy with and without Ampicillin after exposure to ^3H beta-rays at a dose rate of 0.431 Gy/min. The relative biological effectiveness established for ^3H beta-rays to ^<60>Co gamma-rays was 1.23. The reason for the higher effectiveness of ^3H beta-rays as compared to the reference ^<60>Co gamma-rays is discussed in terms of nascent 0 production.
- 日本放射線影響学会の論文
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