Induction of Killer Activity Following Local Irradiation in Intracranial Tumor-Bearing Mice
スポンサーリンク
概要
- 論文の詳細を見る
The induction of killer activity following radiotherapy was studied in intracranial tumor-bearing mice. When local<60>^Co irradiation was administered to intracranial tumor-bearing mice, tumor growth was suppressed and the survival time of the mice was prolonged. The killer activity for 203-glioma target cells gradually increased following the regression of the tumors after irradiation. The maximum killer activity for 203-glioma target cells was o bserved 11 days after irradiation and natural killer activity also increased after irradiation. The killer activity for 203-glioma target cells decreased after treatment with anti-Thy 1.2 and complement. Therefore, killer T-cells may play an important role in this cell-mediated immunity. The relation between the regression of the tumors following radiotherapy and the increase of killer activity may indicate that the effects of radiotherapy are related to the immunological activity of the hosts in addition to the direct cell-killing effects of radiation. These results indicate that the immunological response of patients with brain tumors should be examined both during and after the course of radiotherapy.
- 日本脳神経外科学会の論文
- 1983-07-15
著者
-
YAMASHITA Junkoh
Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa U
-
HANDA Hajime
Department of Neurosurgery, Kyoto University Medical School
-
Otsuka Shin-ichi
Department Of Neurosurgery Kobe City General Hospital
-
Otsuka Shin-ichi
Department Of Neurosurgery Kyoto University Medical School
-
Otsuka Shin-ichi
Department Of Neurosurgery Kitano Medical Research Institute And Hospital:(present Address)departmen
-
TAKEUCHI Juji
Department of Neurosurgery, National Utano Hospital, Kyoto
-
Handa Hajime
Department Of Neurosurgery And Pharmacology Faculty Of Medicine Kyoto University
-
Handa Hajime
Department Of Neurosurgery Kyoto University Medical School
-
Takeuchi Juji
Department Of Neurosurgery Kyoto University Medical School
-
Yamashita Junkoh
Department Of Neurosurgery Kyoto University Medical School
-
Yamashita Junkoh
Department Of Neurosurgery
-
SUDA Kinya
Department of Neurosurgery, Shiga University of Medical Science
-
Suda Kinya
Department Of Neurosurgery Shiga University Of Medical Science
関連論文
- Urinary Excretion of Phenytoin Metabolites, 5-(4'-hydroxyphenyl)-5-Phenylhydantoin and its O-glucuronide in Humans and Analysis of Genetic Polymorphisms of UDP-glucuronosyltransferases
- Detachable Balloon Catheter Systems for Embolization of Cerebrovascular Lesions
- Experimental Studies in Nonsuture End-to-side Microvascular Anastomosis
- Pineal Dermoid Cyst Developing 18 years after Gross Total Removal of a Pineal Mature Teratoma : Case Report
- Cranionavigator Combining a High-speed Drill and a Navigation System for Skull Base Surgery : Technical Note
- Giant Fusiform Aneurysm at the Horizontal Portion of the Middle Cerebral Artery in a Child : Case Report
- Electrothrombosis of Ateriovenous Malformation
- A-14. Prostaglandins and Cerbral Circulation : Effects of Prostaglandins on the Caliber of the Basilar Artery in Cats
- Anomalous Origin of the Anterior Cerebral Artery and Congenital Skull Dysplasia : Case Report
- MR Imaging of Primary Intracranial Malignant Lymphoma
- 2. Central Nervous Monoaminergic System in the Monkey : Location of Monoamine Neurons
- S-II-15. Treatment of Normal Pressure Hydrocephalus following Subarachnoidal Hemorrhage : Sprcial Reference to the Indication of Shunt Operation
- Subependymoma of the Septum Pellucidum Radiologically Indistinguishable from Cavernous Angioma : Case Report
- Nonlinear Theory of Pulse Waves in Blood Vessels
- Stiffness of Cerebral Arteries-Its Role in the Pathogenesis of Cerebral Aneurysms
- A-15. Experimental Studies of Cerebral Aneurysms (the second report).Mechanical Properties of Ccrebral Arteries and Some Hydrodynamical Considerations
- A-103. Hemodynamical Studies of Cerebral Aneurysm (A Preliminary Report) Some Biomechanical Considerations on the Wall Structures of Cerebral Aneurysm and Experimentally Produced Aneurysms
- Granulomatous Pachymeningitis Around the Sella Turcica (Tolosa-Hunt Syndrome) Involving the Hypophysis : Case Report
- ABSORPTION OF THYROTROPIN-RELEASING HORMONE AFTER ORAL ADMINISTRATION OF TRH TARTRATE MONOHYDRATE IN THE RAT, DOG AND HUMAN
- Simulation of Clipping Position for Cerebral Aneurysms Using Three-dimensional Computed Tomography Angiography
- Induction of Killer Activity Following Local Irradiation in Intracranial Tumor-Bearing Mice
- Subfrontal schwannoma without hyposmia - Case report
- Increased expression of deoxyribonucleic acid methyltransferase gene in human astrocytic tumors
- Cervical Osteoplastic Laminotomy Using Autogenous Bone : Technical Note
- Post-irradiation Brain Tumors
- Congenital multiple cavernous angiomas associated with thrombosed arteriovenous malformation of the brain - Case report
- Immunological Correlation of Several Neurogenic Tumors and Mammary Carcinoma in a Syngeneic Rat System
- Fetal Antigenicities in Chemically Induced Rat Neurogenic Tumors
- Trochlear Nerve Neurinoma : Case Report
- 63 63. Serum Proteins in the Edematous Brain Tissue : Study with Fluorescent-Antibody Technique
- Tissue Culture of Chordoma (Its Light-and Electon-Microscopy)
- 14. A Trial of Combined Stereotaxic Approach to Small ArteriovenousMalformation in the Deep Brain Tissue (PROCEEDINGS OF THE Vth ANNUAL MEETING OF THE JAPAN SOCIETY FOR RESEARCH IN STEREOENCEPHALOTOMY)
- S-A-1. An Effective Anterior Spinal Fusion for Tremor at Rest in a Posttraumatic Case
- S-B-2. The Location of Sodium in Normal and Edematous Brain Tissue
- Discussion to 22. Removal of Acoustic Neurinoma through Transtemporal Approach
- 12. Stereotactic Transsphenoidal Cryohypophysectomy in Acromegaly : Clinical and Endocrinological Evalution
- 178. The Roentgen Diagnosis of the Whiplash Injury
- Discussion to 23. In Transsphenoidal Approach to Pituitary Tumors in our Department
- D-17. Idiopathic Occlusive Arterial Disorders in the Cervical Region and the Main Trunks of the Cerebral Arteries in Japan (Special Discussion:Occulsive Arterial Disorders of the Main Trnks of the Cerebral Arteries,Particularly Found in Japan)
- N-1 N-1. Stereotactic Transsphenoidal Hypophysectomy for Advanced Breast Cancer (PROCEEDINGS OF THE IVth ANNUAL MEETING OF THE JAPAN SOCIETY FOR RESEARCH IN STEREOENCEPHALOTOMY)
- Intraorbital Malignant Lymphoma Presenting with Tumor Stain on Angiography : Case Report
- Study on Cases with Posterior Fossa Epidural Hematoma : Clinical Features and Indications for Operation
- A-43. Clinical and Endocrinological Evaluations of Acromegaly : Comparison with Cryogenic and Microsurgical Treatments
- S-III-5. The Role of Phenoxybenzamine in the Treatment of Cerebral Arterial Spasm
- Chronic Subdural Hematoma in the Aged
- Penetrating Injury of the Transverse Sinus by a Nail-gun : Case Report
- Aneurysm Arising at the Triplicate Anterior Communicating Artery : Case Report
- Sex Difference in Cerebrovascular Atherogenesis in Rats-A Preliminaly Report
- Extracellular leakage of stored monoamine in the acute stage of cerebral ischemia : Fluorescence histochemical study
- A-18. Experimental Study on Electrically induced Thrombosis
- 6. Effect of Amantadine on Serotonin Metabolism in Rat Brain
- Monostotic Fibrous Dysplasia of the Left Parietal Bone : Case Report
- Brain Metastasis of Hepatocellular Carcinoma presenting with Hemorrhage : Case Report
- S-G-4 S-G-4. Regeneration of Peripheral Nerves by Irradiated Homografts (Symposium G: Regeneration and Transplantation of the Nervous System)
- 54. Filling-Abnormality (So-Called Vasospasm) Following Rupture of Intracranial Aneurysm:Its Classification and Relation Between Different Patterns and their Prognosis
- 137. A Statistical Survey of Traffic Accidents,especially of Head Injuries in and outside Kyoto in 1966,together with a Comparison with the Data in 1961
- Serial neuroimaging of a growing thrombosed giant aneurysm of the distal anterior cerebral artery: Case report
- Rapid widespread reactions of perivascular cells to focal brain injury in the rat
- Immunohistochemical localization of lysosomal cysteine protease cathepsins B and L in monkey hippocampal neurons after transient ischemia
- 7. Pneumoencephalographic Observation in Patients with Involuntary Movements
- So-called Cerebral Arterial Rete with Idiopathic Occlusive Arterial Disorders in the Main Trunks of the Cerebral Arteries : A report of an Autopsy Case
- S-H-1 S-H-1. The Surgical Treatment of Intracranial Aneurysms and Angiomas, Especially by Means of Electrically Induced Thrombosis (Symposium H: Intracranial Aneurysm and Arterio-venous Malformation)
- Cerebrovascular Diseases from the Viewpoints of Biomechanics and Biorheology
- HISTOCHEMICAL STUDY OF THE CENTRAL MONOAMINE NEURON SYSTEMS IN THE TORTICOLLIS OF CAT (SYMPOSIUM ON HISTOCHEMISTRY AND CYTOCHEMISTRY OF NEUROTRANSMITTERS AND ITS CLINICAL APPLICATION)
- B-13. Effecu of 1-(2-Chloroethyl)-3-Cyclohexyl-1-Nitrosourea (CCNU) on Brain Tumors
- B-4. Tumor Specific Antigen of Brain Tumor
- A-62. Tumor Specific Antigen of Brain Tumor : Carcino-Foetal Antigen and Serum Blocking Factor
- Subarachnoid Hemorrhage Associated With von Willebrand's Disease : Case Report
- Differential Diagnosis and Treatment of Small Subdural Effusion in Children
- The Role of Intracellular Proteases in Brain Tumor
- Intracranial and Spinal Germinomas Occurring Four Years After Spinal Cord Germinoma : Case Report
- 109. Experimental Studies on Electrically Induced Arterial Thrombosis in Dogs,with Special Refence to the Treatment of Intracranial Aneurysms and Angiomas (Proceedings of the XXVth Annual Meeting of the Japan Neurosurgical Society)
- Discussion to Nos.106-110 (Proceedings of the XXVth Annual Meeting of the Japan Neurosurgical Society)
- Effect of High Protein Diet on Cerebral Blood Flow and Cerebrovascular Reactivity in Rats
- Effect of NaCl on Cerebral Stroke and Cerebrovascular Atherogenesis in Rats
- Studies on Stroke in Stroke-Prone Spontaneously Hypertensive Rat (SHRSP):(II) Cerebrovascular Fat Deposition and Cerebrovascular Permeability
- Studies on Stroke in Stroke-Prone Spontaneously Hypertensive Rats (SHRSP):(I) Local Factor Analysis on Stroke
- Experimental Studies on Atherogenesis:(I) Acute Arterial Fat Deposition in Various Hypertensive Rats
- S-A-1. An Effective Anterior Spinal Fusion for Tremor at Rest in a Posttraumatic Case
- Experimental Studies on Atherogenesis:(II) Mechanism of Acute Arterial Fat Deposition in Hypertensive Rats
- Cervical Osteoplastic Laminotomy Using Autogenous Bone —Technical Note—
- Experimental System for Acute Arterial Fat Deposition:Yamori's Preparation I
- Accelerated Induction of Cerebrovascular Lesions in Young Stroke-Prone and -Resistant SHR after Simultaneous Bilateral Carotid Ligation
- Multiple Intracranial Metastases Following Malignant Evolution in Recurrent Pleomorphic Adenoma of the Lacrimal Gland:—Case Report—
- Regional Cerebral Blood Flow in Stroke-Prone SHR:A Preliminary Report
- Electroencephalographic Studies on Stroke in Stroke-Prone SHR:(2) Approach to Stroke
- Discussion to 23