出血性梗塞巣における局所脳循環動態およびCT像 : 実験的研究

概要

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Using a "thalamic infarction model in the dog", it was previously found that hemorrhage infarction can be produced by 6-12 hour occlusion of blood flow, followed by recinculation. In the current study, regional cerebral blood flow (rCBF) and CT scan characteristics of this model were investigated. By means of vascular occlusion, rCBF was reduced roughly to 15 ml/100 gr/min and maintained at that level throughout the period of occlusion. Due to recirculation, transient hyperemia was produced, followed by a decrease in blood flow to below the level found prior to occlusion after several hours. Autopsied sections revealed hemorrhagic infarctions clearly present in the thalamus. Plain CT scans showed low density areas in the right thalamus one hour after recirculation and mild high density areas were seen after intravenous administration of contrast medium. After 2 hours, the high density areas became more marked. Hemorrhagic infarction was clearly found in these models.
日本脳神経外科学会の論文
1981-05-15