HUMAN TROPHOBLAST AND ENDOMETRIAI INTERACTIONS IN VITRO
スポンサーリンク
概要
- 論文の詳細を見る
着床のin vitroモデル実験としてヒトのとロホブラストと子宮内膜細胞を組織培養し,その相互作用を観察した.トロホブラストを子宮内膜細胞と混合培養すると,トロホブラストは、子宮内膜細胞に対して強い親和性を示して強く付着し,トロホブラストを単独で培養した場合に比べて著しく良好な状態で培養された.これは子宮内膜細胞がトロホブラストに対して支持的・栄養的役割をもち,トロホブラストの子宮内膜への付着・発育を促すことを示唆するものと考えられた.培養トロホブラストは活発な細胞運動,飲細胞作用,食細胞作用を有し,子宮内膜上皮細胞に対する浸襲作用,悪性腫瘍細胞に似た子宮内膜細胞群への浸潤作用を示した.このようなトロホブラストの子宮内膜細胞群への浸潤はやがて子宮内膜細胞が脱落膜細胞に似た形態学的変化を遂げることによって阻止された.以上本研究はトロホブラストと子宮内膜細胞との特徴的な相互作用をin vitroで直視下に動的に観察し,着床機序の解明に重要と思われる知見を得た.
- 社団法人日本産科婦人科学会の論文
- 1987-03-01
著者
-
Mori Takahide
Department Of Gynecology And Gbstetrics Faculty Of Medicine Kyoto University
-
Aso Takeshi
Department Of Obstetrics Aud Gylecology Fukui Medical School
-
Aso Takeshi
Department Of Comprehensive Reproductive Medicine Graduate School Tokyo Medical And Dental Universit
-
岸本 善文
Department Of Gynecology And Gbstetrics Faculty Of Medicine Kyoto University
-
TOMINAGA Toshiro
Department of Obstetrics and Gynecology, School of Medicine, Kyoto University
-
KINOSHITA Mikihisa
Department of Gynecology and Obstetrics, Faculty of Medicine, Kyoto University
-
Tominaga Toshiro
Department Of Obstetrics And Gynecology Fukui Medical School
-
Kinoshita Mikihisa
Department Of Gynecology And Gbstetrics Faculty Of Medicine Kyoto University
-
TOMINAGA Toshiro
Department of Obstetrics aud Gylecology, Fukui Medical School
-
MORI Takahide
Department of Gynaecology and Obstetrics, Kyoto University Graduate School of Medicine
関連論文
- P-IS-96 The polyamine and proline pathway in initiation and development of intimal hyperplasia in premenopausal human uterine arteries(Others 2,Group 112,International Session)
- Mediators Involved in Decreasing Peripheral Vascular Resistance With Carbachol in the Rat Hind Limb Perfusion Model
- Triple Marker Screening for Trisomy 21, Trisomy 18 and Open Neural Tube Defects in Singleton Pregnancies of Native Japanese Pregnant Women
- Effect of Estriol on Bone Loss in Postmenopausal Japanese Women : A Multicenter Prospective Open Study
- 43. HPLの母体内分布及び代謝について
- 糖負荷試験における HPL (Human Placental Lactogen) の動態について
- A SIMPLE AND RAPID ASSAY OF SERUM LUTEINIZING HORMONE BY HEMAGGLUTINATION REACTION
- IMMUNOHISTOCHEMICAL ASSESSMENT OF SUPEROXIDE DISMUTASE EXPRESSION IN THE HUMAN ENDOMETRIUM THROUGHOUT THE MENSTRUAL CYCLE
- 妊娠現象の同種移植としての移植免疫学的特異性に関する研究 (母体・胎児間の免疫現象に関する研究)
- Long-term use of dienogest for the treatment of endometriosis
- Immunohistochemical localization of tenascin and ki-67 nuclear antigen in human endometrium throughout the normal menstrual cycle
- Impaired Guanosine 3', 5'-Cyclic Phosphate Production in Severe Pregnancy-Induced Hypertension with High Plasma Levels of Atrial and Brain Natriuretic Peptides
- ENZYME CYTOCHEMICAL AND MORPHOMETRICAL ANALYSES OF GAP JUNCTIONS IN RABBIT OVARIAN GRANULOSA CELLS DURING FOLLICLE MATURATION AND OVULATORY PROCESS
- CYTOCHEMICAL LOCALIZATION OF ACID PHOSPHATASE IN THE RABBIT OVARIAN FOLLICLE
- Bestatin, an Aminopeptidase Inhibitor, Promotes Follicular Growth and Ovulation Suppressed by Stress in Mice
- 119. 絨毛細胞の培養 : とくに子宮内膜細胞との混合培養所見について
- 54. 培養細胞の走査電子顕微鏡による観察
- Diffuse Cystic Change of a Term Placenta with a Normal Newborn
- Ascitic Positive Cytology and Intraperitoneal Metastasis in Ovarian Dysgerminoma
- Spontaneous Resolution of a Postcesarean Arteriovenous Fistula of the Uterine Cervix : The Usefulness of Transvaginal Color Doppler Scanning
- HUMAN EPIDERMAL CELL CULTURE : An Indispensable Tool for the Investigation of Skin Hypermelanosis Occurring during Pregnancy
- (その2) 新生児黄疸と貧血 91.単独抗 E抗体および単独抗 C抗体による新生児溶血性疾患の2治験例 ( 羊水・胎盤・周産期児・婦人科一般群)
- MORPHOLOGICAL STUDIES ON THE ESTABLISHED CELL LINES OBTAINED FROM NORMAL HUMAN DECIDUAL TISSUE OF AN EARLY STAGE OF GESTATION
- A NEW METHOD OF TREATMENT FOR INTRAUTERlNE FETAL HEMOLYTIC ANEMIA CAUSED BY BLOOD TYPE INCOMPATIBILITY
- Changes in Sex Hormones and Calcium Regulating Hormones with Reference to Bone Mass Associated with Aging
- HUMAN TROPHOBLAST AND ENDOMETRIAI INTERACTIONS IN VITRO
- 97. 頚管妊娠の保存的手術2例 (昭和45年臨床大会講演要旨)
- Impaired hyperactivation of human sperm in patients with infertility
- Preovulatory Changes in Morphology of Rabbit Ovarian Follicles
- Changes in Steroidogenesis by Isolated Rabbit Ovarian Follicles in Vitro during the Preovulatory Interval with Emphasis on Active Androgen Production
- Steroid Hormone Formation in Human Ovarian Follicles in Vitro
- Steroid Hormone Formation in Bovine Ovarian Follicles
- 先天性総胆管拡張症による重症黄疸を合併した妊娠の一例
- MODULATION OF HUMAN ENDOMETRIAL STROMAL CELL MORPHOLOGY AND CELL GROWTH ON VARIOUS TYPES OF COLLAGEN SUBSTRATES IN VITRO
- The Effect of Heavy Metal Ions on the in Vitro Development of Mouse Embryos: A Comparison of the Developmental Ability between Hams F-10 and α-MEM
- Oviduct-derived Embryo Growth Promoting Activity: A Comparison of Three Ductal Organs
- Estrous Cycle Independent Embryo Growth Promoting Activity of Mouse Uterus
- Radioimmunoassay method for baboon plasma gonadotropins.