PERIPHERAL CATECHOLAMINE METABOLITES AND FREE TESTOSTERONE IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME
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概要
- 論文の詳細を見る
多嚢胞卵巣症候群は無排卵, 高エストロゲンおよびアンドロゲン血症と不適当なゴナドトロピン分泌とで特徴づけられている. この研究では多嚢胞卵巣症候群と正常月経周期婦人を対象とし, 血中のアンドロゲン状態(free testosterone)とカテコールアミン代謝産物(ドーパミン活性の指標としてDOPAC, アドレナリン活性の指標としてDOPEG)を比較検討した. 多嚢胞卵巣症候群の血中LH, free testosteroneはコントロール群と比較して有意な高値を示し, DOPEG/DOPAC比も有意な高値を示した. また, free testosteroneとDOPEG又はDOPEG/DOPAC比との間には有意な正の相関関係が認められた. ゆえに, in vivoで多嚢胞卵巣症候群患者はアドレナリン活性が優位であり, また, 高アンドロゲンの状態にカテコールアミンが関連していることが示唆された.
- 社団法人日本産科婦人科学会の論文
- 1991-03-01
著者
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Takahashi Kentaro
Department of Internal Medicine, Yamagata prefectural Central Hospital
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吉野 和男
島根医科大学医学部産科婦人科学教室
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KITAO Manabu
Department of Obstetrics and Gynecology, Shimane Medical University
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Kitao Manabu
Department Of Obstetrics And Gynecology Shimane Medical University
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吉野 和夫
島根医科大学医学部産科婦人科学教室
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吉野 和男
島根医大 医
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NISHIGAKI Arata
Department of Obstetrics and Gynecology, Shimane Medical University
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Takahashi Kentaro
Department Of Cardiovascular Medicine Tokyo Medical And Dental University
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吉野 和男
Department Of Obstetrics And Gynecology Shimane Medical University
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EDA Yoshimi
Department of Obstetrics and Gynecology, Shimane Medical University
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Nishigaki Arata
Department Of Obstetrics And Gynecology Shimane Medical University
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Eda Yoshimi
Department Of Obstetrics And Gynecology Shimane Medical University
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Takahashi Kentaro
Department Of Obstetrics And Gynecology Shimane Medical University
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Takahashi Kentaro
Department Of Botany Graduate School Of Science Kyoto University
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TAKAHASHI Kentaro
Department of Allergy and Clinical Immunology, Chiba University Hospital
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