CATECHOLAMINES AND GONADOTROPIN SECRETION IN STERILE WOMEN

概要

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We studied changes in catecholamines, as related to estrogen positive feedback mechanisms, and we measured two catecholamine metabolites (DOPAC, MHPG) in the plasma, using high performance liquid chromatography.In the case of the mean MHPG Ievel, the mean values for two groups in which LH Ievels were from 100 to 200 percent of the basal level of LH and under the basal level of LH were significantly higher than that of a group in which the LH Ievel was double the value for the basal level of LH. But the mean basal DOPAC Ievel showed no significant difference among the three groups. In the good LH reaction group, the MHPG Ievel at 24 and 48 hours after estrogen' injection was signiflcantly higher than the mean basal MHPG level. But in other two groups, the mean MHPG Ievels showed no significant differences. In the case of DOPAC, there was no significant difference in any group. A11 these observations taken together suggested that in vivo, catecholamines may influence the secretion of gonadotropins.
社団法人日本産科婦人科学会の論文
1986-03-01