Exaggerated Placental Site, Consisting of Implantation Site Intermediate Trophoblasts, Causes Massive Postpartum Uterine Hemorrhage: Case Report and Literature Review
スポンサーリンク
概要
- 論文の詳細を見る
Every year, 14 million cases of obstetric hemorrhage occur worldwide, causing 127,000 maternal deaths. About 75% of postpartum hemorrhage cases are due to atonic uterus, which is loss of uterine muscular tone or strength for contraction of the uterus after delivery. The prediction of atonic uterus is therefore important for the prevention of postpartum maternal death. However, prediction of occurrence of atonic uterus is difficult before delivery, because the precise pathophysiological mechanism to trigger this condition remains unclear. Here, we present a case of severe postpartum hemorrhage due to atonic uterus. A 35-year-old woman gave a birth by vaginal delivery to a healthy boy. However, due to intractable massive hemorrhage after the removal of the retained placenta, we performed supravaginal hysterectomy as the best option for survival. Pathological examination showed that implantation site intermediate trophoblasts (ISITs) formed unusually large clumps in the decidua, diagnosed as exaggerated placental site (EPS). EPS is thought to be a condition consisting of an excessive number of ISITs. ISITs are differentiated from a trophoblast lineage in the process of placenta formation. ISITs anchor the placenta to the maternal tissue and are considered to maintain pregnancy, but the postpartum role of these cells remains unclear. Excessive infiltration of ISITs, namely EPS, may cause postpartum atonic uterus. In this article, we also reviewed the literatures on EPS. The present case and other reported cases indicate that EPS causes mass formation in the uterus, continuous uterine bleeding, and massive hemorrhage, resulting in hysterectomy.
- 東北ジャーナル刊行会の論文
著者
-
Murakami Takashi
Department Of Cardiology Okayama University School Of Medicine
-
Okabe Hidetoshi
Department Of Clinical Laboratory Medicine And Division Of Diagnostic Pathology
-
Tsuji Shunichiro
Department Of Obstetrics And Gynecology Shiga University Of Medical Science
-
Kita Nobuyuki
Department Of Obstetrics And Gynecology Shiga University Of Medical Science
-
Ono Tetsuo
Department Of Obstetrics And Gynecology Shiga University Of Medical Science
-
Kaku Shoji
Department Of Obstetrics And Gynecology
-
Kimura Fuminori
Department Of Obstetrics And Gynecology Shiga University Of Medical Science
-
Takebayashi Akie
Department Of Obstetrics And Gynecology Shiga University Of Medical Science
-
Yamanaka Akiyoshi
Department Of Obstetrics And Gynecology Shiga University Of Medical Science
-
TAKAHASHI Kentaro
Department of Allergy and Clinical Immunology, Chiba University Hospital
-
Takahashi Akimasa
Department of Obstetrics and Gynecology, Shiga University of Medical Science
関連論文
- OJ-007 Blunted QT Prolongation to Sudden R-R Prolongation in Brugada Syndrome Patients with Coved ST Elevation(Arrhythmia, diagnosis/ Pathophysiology/ EPS(03)(A),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation So
- OE-392 Experience of Intravenous Amiodarone in Japanese Patients with Lethal Arrhythmias Refractory to Other Antiarrhythmic Drugs(Emergency care/CPR(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Mechanism of Hypertension Induced by Chronic Inhibition of Nitric Oxide in Rats
- Biotitization of vermiculite under hydrothermal condition
- PJ-060 Sequential Changes in Left Atrial Function After Pulmonary Vein Isolation in Patients with Atrial Fibrillation(Arrhythmia, therapy-15, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-037 Efficacy of Prone Position Image by Multidetector Computed Tomography for Detecting Pseudo Pulmonary Vein Stenosis(Arrhythmia, diagnosis/pathophysiology/EPS-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-297 Elevated Levels of 8-Hydroxy-2-Deoxyguanosine in Serum and Myocardium of Patients with Dilated Cardiomyopathy(Cardiomyopathy, Clinical 6 (M) : OE37)(Oral Presentation (English))
- Mode of frequency distribution of external work efficiency of arrhythmic beats during atrial fibrillation remains normal in canine heart
- High Mechanical Efficiency of Left Ventricular Arrhythmic Contractions during Atrial Fibrillation
- Variable Unstressed Volume Keeps Normal Distributions of Canine Left Ventricular Contractility and Total Mechanical Energy under Atrial Fibrillation
- Predictability of O_2 Consumption from Contractility and Mechanical Energy of Absolute Arrhythmic Beats in Canine Heart
- Prone Position is Essential for Detection of Pulmonary Vein Pseudostenosis by Enhanced Multidetector Computed Tomography in Patients Who Undergo Pulmonary Vein Isolation
- PE-496 Sequential Changes on Left Atrial Function After Repeat Pulmonary Vein Isolation in Patients with Paroxysmal Atrial Fibirllation(Arrhythmia, therapy(15)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Socie
- OE-038 Autonomic Modification Associated with Radiofrequency Pulmonary Vein Isolation Plays an Important Role for Cure of Atrial Fibrillation(Arrhythmia, therapy-1 (A) OE7,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the J
- OE-117 Topographic Visualization of Cardiac Venous System and Surrounding Structures Using 64-multislice CT for Cardiac Resychronization Therapy and Catheter Ablation(CT/DSA-01, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Aortic and Mitral Valve Replacement in an 83-year-old female : 3 years follow-up of 16 mm bileaflet valve at the aortic position
- OE-079 Increased Cardiomyocyte Stiffness of the Transverse Direction in the Rat Heart with Hypertrophy Induced by Chronic β-Adrenergic Stimulation(Heart failure, basic(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Ci
- OE-201 Increasing Heart Rate Increased Residual Actin-Myosin Interaction without Raising End-diastolic Left Ventricular Pressure in Beating Rat Heart(OE34,Cardiac Function (Basic) (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The J
- Isoproterenol-Induced Hypertrophied Rat Hearts : Does Short-Term Treatment Correspond to Long-Term Treatment?
- FRS-114 Increasing preload attenuates crossbridge formation under hypoxia(New Concepts for Assessing Cardiac Function(M),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Effects of a Novel Histone Deacetylase Inhibitor, N-(2-Aminophenyl) Benzamide, on a Reversible Hypertrophy Induced by Isoproterenol in In Situ Rat Hearts
- OE-202 Higher Heart Rate Attenuates the Actin-Myosin Interaction in LV Free Wall(Cardiac function, basic/clinical-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-556 Impaired Coronary Capillary Flow with Decreased Glycocalyx Thickness and Irregular Inner Wall Remodeling in Right Ventricle of Pulmonary Hypertensive Rats(Coronary circulation, basic/clinical-3 (IHD) PE95,Poster Session (English),The 70th Anniversa
- Sulfaphenazole, an Inhibitor of Cytochrome 2C9, Ameliorates Impaired NO-mediated Coronary Arteriolar Vasodilation in Spontaneously Hypertensive Rats-Direct In Vivo Visualization(Coronary Circulation, Basic/Clinical 3 (IHD), The 69th Annual Scientific Meet
- Real-time Monitoring of Vascular Metabolic Components with Microsensor System Based on Ion-sensitive Field Effect Transistor(Metabolism/Biochemistry/Energetics 2 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Transmurally Difference in Crossbridge Dynamics and Sarcomere Shortening during Relaxation of Isovolumic Beat(Cardiac Function, Basic/Clinical 3 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PE-227 Alterations of Heart Rate and Heart Rate Variability after Slowpathway Radiofrequency Catheter Ablation. : Comparison during daytime with nighttime(ECG/Body Surface Potential Mapping/Holter 4 (A) : PE39)(Poster Session (English))
- Exponential-Exponential Cosine Fitting of Blood Pressure Decay by a Long-Acting Calcium Channel Blocker, Amlodipine, Using Home-Blood Pressure Measurement
- Relationship between R-R Interval (RR-l) and Maximal-Flow-Velocity of Aorta as a Marker of Cardiac Performance in Patients with Chronic Non-Valvular Atrial Fibrillation (NVAF)
- Spectrum Analysis of Beat-by-Beat Blood Flow of Aorta (Ao), Pulmonary Artery (PA) in Sinus Node Rhythm (SNR), Chronic Non-Valvular Atrial Fibrillation (NVAF)
- Exponential Hyperbolic Sine Function Fitting of Heart Rate Response to Constant Load Exercise
- PJ-381 Predictors of Sleep Apnea in Patients with Cardiovascular Disease(Heart failure, clinical-11, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-568 Fractional Flow Reserve (FFR) by Fullback (PB) Method to Predict Restenosis and Target Lesion Revascularization : Comparison with Conventional (C) Method(Restenosis after Angioplasty, Basic/Clinical 7 (IHD) : PJ95)(Poster Session (Japanese))
- Nicorandil Reduces the Incidence of Minor Enzyme Elevation after Percutaneous Coronary Intervention (PCI)
- PJ-167 Increase of Escape Rhythms with Years after Radiofrequency Ablation of Atrioventricular-junction Combined with Pacemaker (Ablate and Pace) in Atrial Fibrillation(Arrhythmia, Non-Pharmacological Therapy 6 (A) : PJ28)(Poster Session (Japanese))
- Is Direct Cell-to-Cell Contact Needed to Improve Embryonic Development in Co-Culture?
- Endomyometriosis arising in the uterosacral ligament : A case report including a literature review and immunohistochemical analysis
- Growth Hormone Improves Mouse Embryo Development In Vitro, and the Effect Is Neutralized by Growth Hormone Receptor Antibody
- Effect of Nicorandil on Slow Flow and No Reflow during Rotational Atherectomy Compared with Those of Verapamil
- Clinical pitfalls of pain recurrence in endometriosis arising in the posterior vaginal fornix
- Management of the Pain Associated with Endometriosis : An Update of the Painful Problems
- Clinical Manifestations and Outcomes of Parvovirus B19 Infection during Pregnancy in Japan
- Prolonged relaxant effects of vecuronium in patients with deliberate hypermagnesemia : time for caution in cesarean section
- Lactation and Risk of Endometrial Cancer in Japan : A Case-Control Study
- Appearance of Abnormal Electrocorticogram Patterns during Umbilical Cord Compression in Sheep Fetus
- Safe techniques in surgery for hysteroscopic myomectomy
- Microtubule organization during rabbit fertilization by intracytoplasmic sperm injection with and without sperm centrosome
- Isolated Torsion of the Distal Part of the Fallopian Tube in a Premenarcheal 12 Year Old Girl : A Case Report
- Successful Pregnancy after Myomectomy Using Preoperative Adjuvant Uterine Artery Embolization
- The Cul-de-sac Packing Method with a Metreurynter in Gynecologic Gasless Laparoscopy
- The Current Status of Gynecological Laparoscopic Surgery in Educational Facilities in Japan
- Evidence for the Proteolytic Cleavage of Versican in Infarct Heart (Old Myocardial Infarction/Remodeling 2 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-065 Increments of serum chemokine interferon-gamma inducible protein 10 (IP-10) levels correlated with left ventricular function in acute myocardial infarction patients(Acute Myocardial Infarction, Clinical (Pathophysiology) 3 (IHD) : PJ11)(Poster Sess
- OE-312 Vasl1 (Vascular Link Protein-1) Is a Novel Extracellular Matrix Protein Limited To Vessels and Is Upregulated in Pressure Overload Heart(Hypertension, Basic 3 (H) : OE39)(Oral Presentation (English))
- OE-278 Low dose of Cerivastatin increased microvessel formation and induced angiogenesis in conjunction with attenuating antiangiogenic protein in rat myocardial infarction(Cardiovascular Pharmacology, Basic/Clinical 1 (H) : OE34)(Oral Presentation (Engli
- OE-072 Serum Antibodies to Human Heat Shock Protein 60 Is Elevated in Subjects With Unstable Angina Pectoris(Acute Coronary Syndrome, Basic/Clinical 3 (IHD) : OE9)(Oral Presentation (English))
- FRS-078 ADAMTS-1, A Disintegrin And Metalloprotease with ThromboSpondin motifs-1, Is a Novel Hypoxic Immediate Gene Expressed by Endothelial Cells(NO and Cardiovascular System (H) : FRS10)(Featured Research Session (English))
- PE-046 Newly formed relatively large vessels after myocardial infarction express matricellular protein, Thrombospomndin-1 (TSP-1) in rats : Comparison with real-time RT-PCR analysis(Endothelium/NO 1 (H) : PE8)(Poster Session (English))
- Endothelial Cells of Newly Formed Vessels in the Border Zone of Myocardial Infarction Express Proteoglycan Decorin and Biglycan
- Metalloprotease ADAMTS-1 Was Rapidly Expressed by Endothalial Cells in Acute Myocardial Infarction and Its Quantitative Analysis by Real-Time PCR
- Dynamic Induction of ADAMTS1 Gene in the Early Phase of Acute Myocardial Infarction
- Spatial changes of gelatinolytic activity in myocardial infarction in rats
- Cervical Cytologic Examination During Physical Checkup of Pregnant Women : Cervical Cancer Screening in Women Under the Age of Thirty
- High serum Brain Natriuretic peptide levels as a marker of risk for silent stroke in patient with non-valvular Af
- OE-386 Elevated Oxidative Stress and Ventricular Fibrillation Episode in Patients with Brugada Syndrome.(Arrhythmia, diagnosis/Pathophysiology/EPS(02)(A),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Increased O_2 consumption in excitation-contraction coupling in hypertrophied rat heart slices related to increased Na^+-Ca^ exchange activity
- Positive inotropic effect of nicorandil in adult rats in situ
- PJ-382 Real-time Monitoring of Cultured Myocytes Acidification at Different Temperature with Microsensor System Based on Ion-sensitive Field Effect Transistor(Metabolism/Biochemistry/Energetics 2 (IHD) : PJ64)(Poster Session (Japanese))
- PE-137 Comparison of Age-matched Endothelium-derived Relaxation Factors in Coronary Microcirculation between Normotensive and Spontaneously Hypertensive Rats : Direct In Vivo Visualization(Coronary Circulation, Basic/Clinical 1 (IHD) : PE24)(Poster Sessio
- FRS-041 Coronary Microvascular Endothelial Dysfunction with Decreased Glycocalyx Thickness and Increased Reactive Oxygen Species in Spontaneously Hypertensive Rats(Vascular Biology in Endothelial Cells (basic), The 71st Annual Scientific Meeting of the Ja
- OJ-008 Usefulness of the Hot-Bath Test in Brugada Sydrome(Arrhythmia, diagnosis/ Pathophysiology/ EPS(03)(A),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Mitral Valve Replacement through Right Thoracotomy after Previous Coronary Artery Bypass Grafting : The Usefulness of Brachial Artery Cannulation, Perfused Ventricular Fibrillation with Moderate Hypothermia, and Minimal Dissection Techniques
- Intracerebellar Penetrating Injury and Abscess Due to a Wooden Foreign Body
- Nicorandil decreased infarct size with enhancement of Serum interleukin 6 levels in patients with acute myocardial infarction after successful reperfusion
- Bilateral Areolar Sebaceous Hyperplasia in a Male
- Rapid increase of matrix adhesive glyocprotein, thrombospondin-1 (TSP-1) mRNA in rat myocardial infarction (MI) and its localization
- Heparin Binding Epidermal Growth Factor-like Growth Factor (HB-EGF) is Increased in Myocardial Infarction (MI) : Enhancement by Reperfusion and Auto-induction by Recombinant Protein
- Telomerase Activity in Normal Ovaries and Premature Ovarian Failure
- Pulmonary veno-occlusive disease associated with partial anomalous pulmonary venous connection
- Development of a pulsatile flow-generating circulatory-assist device
- Endothelial Cells of Newly Formed Vessels Express Osteonectin mRNAs in the Border Zone of Myocardial Infarction (MI) in Rats
- Chemokine Receptor CXCR-3 Was Up-regulated in Rat Myocardial Infarction(MI) : Anasysis of cDNA Array and Quantitative Expression by Real Time PCR
- Tissue Inhibitor of Metalloproteinase-2 Localization in Myocardial Infarction (MI) in Rats : Another Role as an Activator for Metalloproteinase-2
- Iatrogenic Paraplegia Caused by Surgicel Used for Hemostasis During a Thoracotomy:Report of a Case
- Cosmetic Approach for Correction of Simple Congenital Heart Defects in Female Patients
- A Reproducible LPE Growth of High-Quality In_Ga_xP_As_y Layers on GaAs by the Control of Phosphorus Vapor on the Substrate
- Magnetic Resonance Imaging of Morphological and Functional Changes of the Uterus Induced by Sacral Surface Electrical Stimulation
- SCN5A Mutation Is Associated With Early and Frequent Recurrence of Ventricular Fibrillation in Patients With Brugada Syndrome
- Expression profiling of cancer-related genes in human keratinocytes following non-lethal ultraviolet B irradiation
- In Situ Observation of Bovine Serum Albumin-Adsorbed Stearic Acid Monolayer by Brewster Angle Microscopy
- Comparison of Changes in the Transversus Abdominis and Neighboring Fascia in Subjects With and Without a History of Low Back Pain Using Ultrasound Imaging
- Formation of linde F zeolite by KOH treatment of coal fly ash
- Emerging views on the evolution of atmospheric oxygen during the Precambrian
- Prenatal Diagnosis of Sirenomelia in the Late Second Trimester with Three-Dimensional Helical Computed Tomography
- Nonlinear dependence of the oxidation rate of Fe(II) on dissolved oxygen under low-O_2 conditions in aqueous solutions
- Formation of rare earth phosphate minerals in 2.45-Ga paleosol
- Primate Model Research for Endometriosis
- Biotitization of vermiculite under hydrothermal condition.
- Size distribution of ferrihydrite aggregate and its implication for metal adsorption and transport
- Long-term outcome, including pregnancy rate, recurrence rate and ovarian reserve, after laparoscopic laser ablation surgery in infertile women with endometrioma