水環境中変異原物質の運命 : シンポジウム : I. 環境汚染変異原

概要

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In order to clarify the fate of mutagens in a water environment, mutagenic characteristics of water from a river basin of the Biwa Lake-Yodo river as a typical river was investigated. Potential pollutant-sources were sought for municipal stream waters, e, g., effluents of nightsoil and sewage treatment plants, road runoff and rain fall. XAD-2 resin and blue rayon were used to recover mutagens from the Yodo river. The Ames Salmonella/microsome assay with TA98, TA100 and YG strain series was used to test XAD-2 resin and blue rayon concentrates recovered from the river water ; this revealed indirect mutagenicity toward TA98. Frameshift mutagens among directly mutagenic nitroarenes and indirectly mutagenic aminoarenes and heterocyclic amines may derive from potential pollutant-sources described above. The possible fate of mutagens in a water environment was discussed. (This paper, in a session chaired by Teruhisa Hirayama and Keiji Wakabayashi, was presented to the symposium "Mutagenicity of environmental pollutants", organized by Teruhisa Hirayama, at the 27^<th> annual meeting of the Environmental Mutagen Society of Japan, and held at the Mielparque Osaka in Osaka, Japan, November, 24-26, 1998.)
日本環境変異原学会の論文
1999-07-12