DDS医薬品の臨床使用 : リポPGE_1製剤の輸液配合使用の実態調査

概要

論文の詳細を見る
As DDS drugs with various drug delivery functions are often prescribed under in combination with a widerange of concurrent drug therapies. drug information closely related to its clinical usage is required to guarantee the appropriate multiple pharmaceutical functions of DDS drugs. We surveyed the actual concurrent therapy of Iipo-PGEI (Palux^%<gt;[!OR] >inj. and Lipie^%<gt;[!OR] >, a targeting-type DDS. with various aqueous infusions at both Okayama University Hospital and Fukui Medical School Hospital. The term of the survey, which was done by evaluating the prescription records. and the total number of prescriptions were 14 months and l.005 prescriptions, respectively. Lipo-PGE_1 was scarcely administered without any concurrently prescribed infusions. Although lipo-PGE_1was mostly diluted with Glucose Injection or Isotonic Sodium Chloride Solution. some electrolyte infusions were also concurrently prescribed with Lipo-PGE_1 in some cases. The magnification of the dilution and the administration route seemed to be related each other. The data revealed in this report ave considered to be useful for a clinical usage-based assessment system to obtain further information guaranteeing the drug delivery function of Lipo-PGE_1 from both a pharmaceutical and phamlacodynamic viewpoint one word.
1999-08-10