うつ病の消化器症状(各科におけるうつ病)

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For the last 3 years, there were 105 patients who were diagnosed as having a depression or being in a depressive state at the psychosomatic clinic of our department. The frequency of these patints was 14.5% of all patients who consulted with the clinic. With regard to the age distribution of these patients, highest incidence was seen in 40-50 years of age, which was followed by those of 50-60 years of age. However, there were about 20 patients whose ages were between 15-25. The majority of these adolescent patients had been diagnosed as having school phobis, and had been absent from school or given up school, because of easy fatigability, or stool abnormality, loss of volition for study, difficult awaking, stc. Among the digestive symptoms in patients with depression or depressive state, anorexia was most frequent. This was followed by the symptoms such as nausea, vamiting, abdominal discomfort, constipation, abdominal pain and diarrhea. These patients were treated mainly with antidepressants and antianxiety drugs. The improvement rate of symdroms was studies by a questionaire. It was discovered that a higher improvement rate was obtained in abdominal pain, nausea, vomiting and diarrhea than in the other symptoms. Moreover, a patho-physiological study was conducted to examine why digestive symptoms were complained in patients with depression or depressive state. Hyper motility with hypersecretion of the gastrointestinal tract was demonstrated in more than 75% patients. This was proven with barium enema examination and EMG of the colon. However, hypokinetic biliary dyskinesia were seen commonly in these patients. The physiologic or biochemical mechanism for the findings remained to be further elucidated.
日本心身医学会の論文
1978-02-01

うつ病の消化器症状(各科におけるうつ病)

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