脊髄小脳変性症における電気生理学的検討 : 神経伝導速度と体性感覚誘発電位

概要

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Nerve conduction velocity (NCV) and somatosensory evoked potentials (SSEP) were examined in 14 patients with Spinocerebellar degeneration (SCD); 9 patients with Olivo-ponto-cerebellar atrophy (OPCA) and 5 patients with the Holmes type of cerebellar atrophy. An abnormality of NCV was observed in 10-30％of SCD patients. A central conduction time, calculated from the latency of SEP which was evoked by median nerve stimulation, was prolonged in one patient with OPCA and in one patient with the Holmes type. In patient with the Holmes type, the value of NCV had a negative correlation with the duration of the illness (r=-0.9, p <0.05). These results suggest that an incidence of peripheral neuropathy in SCD patient increases in the advanced stage of the illness.
信州大学の論文