<原著>牛血清由来のEBウイルス遊離阻止因子の細胞およびウイルスにおよぼす影響 : 電子顕微鏡による観察

概要

論文の詳細を見る
Morphological evidence has been obtained by electron microscopy in support of the previous study that adult bovine serum added in culture medium of P3HR-I cell line, the main source of infectious EB virus (EBV), reduces the amount of EBV released into culture fluid from host cells. In the presence of bovine serum extracts the number of virus particles in the culture fluid of P3HR-I cell cultures was significantly reduced, althouqh the maturation, infectivity and morphology of the released virus were scarcely influenced. Thin sections of P3HR-I cells indicated that many virus particles were contained in the vacuoles formed in the cytoplasm of cells and that most of these virus particles linked to vacuole membranes with their tail-like structures. These suggest that the release of virus from cells is inhibited by cellular membranes changed in quality in the presence of bovine serum extracts.
近畿大学の論文
1977-06-25