A case of nonketotic hyperosmolar coma with pontine and extra-pontine myelinolysis on magnetic resonance imaging
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概要
- 論文の詳細を見る
We present a patient with nonketotic hyperosmolar coma who exhibited extra-pontine myelinolysis as demonstrated by the findings including magnetic resonance imaging (MRI). The lesions appeared as widespread symmetrical hyperintensities that involved the subcortical white matter of the frontal, temporal, and parietal lobes. Thinning of the cerebral cortices was observed. The center of the pons was only slightly affected. The patient ultimately died of pneumonia. The abrupt changes in serum sodium concentration and/or osmolarity, induced not only by treatment of hyponatremia, but by alteration to the hypernatremic state, may have contributed to the development of pontine and extra-pontine myelinolysis. To our knowledge, this is the first case in which the MRI results corresponded to previously reported autopsy findings of extra-pontine form by Okeda et al. in pontine and extra-pontine myelinolysis.
- 島根大学の論文
著者
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Kobayashi Shotai
島根大学 医学部神経内科
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KOBAYASHI Shotai
Department of Internal Medicine III, Shimane Medical University
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YAMAGUCHI Shuhei
Department of Internal Medicine III, Shimane Medical University
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Kobayashi Shotai
Department Of Neurology Hematology & Rheumatology School Of Medicine Shimane University
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Okada Kazunori
Biotechnology Research Center, University of Tokyo
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OKADA Kazunori
Department of Biology, Tokyo Gakugei University
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Kobayashi S
Shimane Medical Univ. Izumo Jpn
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Kono Naoto
Department of Internal Medicine III,Shimane Medical University
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Yamagata Shingo
Department of Internal Medicine III,Shimane Medical University
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Okada Kazunori
Biotechnology Res. Center Univ. Of Tokyo
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Yamaguchi Shuhei
Department Of Internal Medicine Iii Shimane Medical University
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Kobayashi Shotai
Department Neurology Hematology & Rheumatology Shimane University School Of Medicine
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Kono Naoto
Department Of Internal Medicine Iii Shimane Medical University
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Okada Kazunori
Biotechnology Research Center University Of Tokyo
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Yamagata Shingo
Department Of Internal Medicine Iii Shimane Medical University
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