Clinical Characteristics of First-Ever Atherothrombotic Infarction or Lacunar Infarction with Hyperlipidemia (J-STARS-C) : An Analysis of Data from the Stroke Data Bank of Japan

スポンサーリンク

概要

• 論文の詳細を見る

• Objective The clinical trial, Japan Statin Treatment Against Recurrent Stroke (J-STARS), is being carried out to investigate the efficacy of statin treatment against recurrent stroke. To participate in J-STARS, patients must have a past history of ischemic stroke excluding cardioembolic events, and must be clinically diagnosed with hyperlipidemia (HL). Before starting J-STARS, we needed to be aware of the clinical characteristics of the patients who were eligible to participate in this study.Methods Between 1999 and 2002, 7,149 patients with ischemic stroke were enrolled in a stroke data bank developed by the Japan Standard Stroke Registry Study Group. From this, we acquired the data on 1,487 patients with first-ever atherothrombotic infarction (ATI) or lacunar infarction (LI) with a satisfactory functional outcome on discharge.Results Patients with HL were significantly younger (65.3±11.0 vs 68.4±10.9, p<0.0001) and showed a higher frequency of concomitant hypertension (70.9% vs 61.0%, p=0.0002), diabetes mellitus (42.2% vs 25.7%, p<0.0001) or both (31.7% vs 16.4%, p<0.0001) compared to those without HL. The ratio of ATI to LI and the frequency of prior ischemic heart disease (IHD) did not differ between the 2 groups. Among 467 patients with HL, 52.7% did not receive treatment on admission.Conclusion ATI or LI patients with HL had an earlier age of onset and higher frequency of other lifestyle-related diseases, and this probably includes many with metabolic syndrome, whereas the frequency of IHD was not different between these 2 groups.

• 社団法人　日本内科学会の論文
• 2005-12-01

著者

• Matsumoto Masayasu

  Department Of Clinical Neuroscience And Therapeutics Hiroshima University Graduate School Of Biomedi

• KOBAYASHI Shotai

  Department of Internal Medicine III, Shimane Medical University

• NOMURA Eiichi

  Department of Neurology, Tsuchiya General Hospital of Akane Medical Corporation

• Nomura Eiichi

  Department Of Neurology Suiseikai Kajikawa Hospital

• Nomura Eiichi

  Department Of Materials Science And Engineering The Graduate School At Nagatsuta Tokyo Institute Of

• KOHRIYAMA Tatsuo

  Department of Clinical Neuroscience and Therapeutics, Hiroshima University

• Kobayashi Shotai

  Department Of Neurology Hematology And Rheumatology Shimane University School Of Medicine

• Kobayashi Shotai

  Department Neurology Hematology & Rheumatology Shimane University School Of Medicine

• Kohriyama Tatsuo

  Department Of Clinical Neuroscience And Therapeutics Hiroshima University Graduate School Of Biomedi

• Matsumoto Masayasu

  Department Of Clinical Neuroscience And Therapeutics Hiroshima University Graduate School Of Biomedi

• Matsumoto Masayasu

  Department Of Clinical Neuroscience And Therapeutics Graduate School Of Biomedical Science Hiroshima University

• Matsumoto Masayasu

  Department of Clinical Neuroscience and Therapeutics Division of Integrated Medical Science, Graduate School of Biomedical Sciences, Hiroshima University

関連論文

• Frequency and Pathogenesis of Silent Subcortical Brain Infarction in Acute First-ever Ischemic Stroke
• Cerebral Infarction and Patent Foramen Ovale (PFO) in the Elderly : Is PFO the Culprit or Not?
• Improvement of a Pulse Generator for the Atom-Probe: Doubling of Pulse-Voltage
• Association between central systolic blood pressure, white matter lesions in cerebral MRI and carotid atherosclerosis
• Diagonal Ear-Lobe Crease is Correlated With Atherosclerotic Changes in Carotid Arteries
• Clinical Characteristics of First-Ever Atherothrombotic Infarction or Lacunar Infarction with Hyperlipidemia (J-STARS-C) : An Analysis of Data from the Stroke Data Bank of Japan
• Electrophysiological assessment of Choto-san treatment for stroke patients with mild cognitive impairments
• Effect of One-Shot Intravenous 0.42 Mega Unit Urokinase Therapy in Patients With Acute Ischemic Stroke
• Deterioration of Vascular Dementia Caused by Recurrent Multiple Small Emboli from Thoracic Aortic Atheroma
• Analysis of Subarachnoid Hemorrhage According to the Japanese Standard Stroke Registry Study : Incidence, Outcome, and Comparison With the International Subarachnoid Aneurysm Trial(EBM of Neurosurgical Disease in Japan)
• A case of nonketotic hyperosmolar coma with pontine and extra-pontine myelinolysis on magnetic resonance imaging
• Evaluation of applied cases of thrombolytic therapy against ultra-acute ischemic stroke : Using the Japanese Standard Stroke Registry Database
• TEMPORAL ARTERITIS WITH SJOGREN'S SYNDROME
• NUMBNESS OF THE RIGHT HAND AS THE INITIAL SYMPTOM IN CREUTZFELDT-JAKOB DISEASE
• UNILATERAL OCULOMOTOR NERVE PALSY IN PROGRESSIVE SYSTEMIC SCLEROSIS
• Episcleritis Associated with Pigmentary Retinal Degeneration in an HTLV-I Carrier
• FRS-102 Event rates of Japanese patients with atherothrombosis : Results from the REduction of Atherothrombosis for Continued Health (REACH) Registry(Clinical Frontiers in Atherosclerosis(IHD),Featured Research Session,The 72nd Annual Scientific Meeting o
• Prevalence, Awareness and Treatment of Cardiovascular Risk Factors in Patients at High Risk of Atherothrombosis in Japan : Results From Domestic Baseline Data of the REduction of Atherotherombosis for Continued Health(REACH) Registry
• 5 International and National Cohort Study for the Clarification of the Characteristic of the Japanese Patients of Atherothrombosis(Comparison between Domestic and Overseas Clinical Evidence in Cardiology,Symposium 9 (SY9) (H),The 70th Anniversary Annual S
• Characterization of Japanese Patients with Atherothrombosis by Participating in the International Registry of REACH (REduction of Atherothrombosis for Continued Health)(How to Make Japanese Original Evidence in Cardiology, The 69th Annual Scientific Meeti
• Autoimmune-associated hemophagocytic syndrome
• Hemophagocytic Syndrome, a Possible Association with Aplastic Anemia?
• Embolic Cerebral Infarction Caused by Intraluminal Thrombus in the Carotid Siphon Successfully Treated With Combination of Anticoagulant and Antiplatelet Drugs
• Critical Analysis of Hemodynamic Insufficiency by Head-up Tilt in Patients With Carotid Occlusive Disease
• Future Aspects of Gene Therapy in Acute Ischemic Stroke
• Hemodynamic Influences of Losartan on the Brain in Hypertensive Patients
• Clinical significance of cerebrovascular reserve in acetazolamide challenge : Comparison with acetazolamide challenge H_2O-PET and Gas-PET
• Carotid Atherosclerosis as a Risk Factor for Complex Aortic Lesions in Patients With Ischemic Cerebrovascular Disease
• Evaluation of the use of a standard input function for compartment analysis of [^I]iomazenil data : factors influencing the quantitative results
• Smoking Habit as a Putative Risk Factor for Carotid Plaque Ulcers
• Clinical Usefulness of Duplex Ultrasonography for the Assessment of Renal Arteriosclerosis in Essential Hypertensive Patients
• EFFECT OF BLOOD PRESSURE LEVELS ON CAROTID ATHEROSCLEROSIS IN HIGH RISK PATIENTS FOR ATHEROSCLEROSIS
• Relationship between neuronal loss and tangle formation in neurons and oligodendroglia in progressive supranuclear palsy
• 2 How to Protect the Brain with Anti-hypertensive Agents against Stroke and Dementia(Practice of Hypertension management, Looking into one's heart,Roundtable Discussion 3 (RT3) (H),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
• The Present State of Acute Ischemic Stroke Therapy in Japan
• Is Hyperhomocysteinemia Related to Widowers' Stroke Syndrome?
• Is Type 2 Diabetes a Risk Factor for Silent Ischemic Brain Lesion?
• Clinical relevance of central systolic blood pressure and augmentation index : comparison with carotid echo parameters
• Sequential Changes in von Willebrand Factor and Soluble Thrombomodulin in Acute Ischemic Stroke
• Two Cases of Cerebral Embolism Caused by Apical Thrombi in Midventricular Obstructive Cardiomyopathy
• Randomized, Multicenter, Warfarin-Controlled Phase II Study of Edoxaban in Japanese Patients With Non-Valvular Atrial Fibrillation
• Rivaroxaban vs. Warfarin in Japanese Patients With Atrial Fibrillation : The J-ROCKET AF Study
• Akinetic Mutism Caused by HIV-associated Progressive Multifocal Leukoencephalopathy was Successfully Treated with Mefloquine: A Serial Multimodal MRI Study
• The optimal timing of antihypertensive medication administration for morning hypertension in patients with cerebral infarction
• Cancer-associated ischemic stroke is associated with elevated D-dimer and fibrin degradation product levels in acute ischemic stroke with advanced cancer
• Safety and Efficacy of Adjusted Dose of Rivaroxaban in Japanese Patients With Non-Valvular Atrial Fibrillation : – Subanalysis of J-ROCKET AF for Patients With Moderate Renal Impairment –
• Management and Two-Year Long-Term Clinical Outcome of Acute Coronary Syndrome in Japan:– Prevention of AtherothrombotiC Incidents Following Ischemic Coronary Attack (PACIFIC) Registry –
• Cerebral Sinus Thrombosis and Heparin-induced Thrombocytopenia in a Patient with Paroxysmal Nocturnal Hemoglobinuria
• Cytotoxic Edema in Neuro-Behcet's Disease ?
• Management and Two-Year Long-Term Clinical Outcome of Acute Coronary Syndrome in Japan : Prevention of AtherothrornbotiC Incidents Following Ischemic Coronary Attack (PACIFIC) Registry
• Safety and Efficacy of Adjusted Dose of Rivaroxaban in Japanese Patients With Non-Valvular Atrial Fibrillation : Subanalysis of J-ROCKET AF for Patients With Moderate Renal Impairment
• Blood pressure variability and prognosis in acute ischemic stroke with vascular compression on the rostral ventrolateral medulla (RVLM)
• Angiotensin II induces human astrocyte senescence through reactive oxygen species production
• Lifetime risk of stroke and impact of hypertension : estimates from the adult health study in Hiroshima and Nagasaki

もっと見る 閉じる

スポンサーリンク