Clinical Characteristics of First-Ever Atherothrombotic Infarction or Lacunar Infarction with Hyperlipidemia (J-STARS-C) : An Analysis of Data from the Stroke Data Bank of Japan
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概要
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Objective The clinical trial, Japan Statin Treatment Against Recurrent Stroke (J-STARS), is being carried out to investigate the efficacy of statin treatment against recurrent stroke. To participate in J-STARS, patients must have a past history of ischemic stroke excluding cardioembolic events, and must be clinically diagnosed with hyperlipidemia (HL). Before starting J-STARS, we needed to be aware of the clinical characteristics of the patients who were eligible to participate in this study.Methods Between 1999 and 2002, 7,149 patients with ischemic stroke were enrolled in a stroke data bank developed by the Japan Standard Stroke Registry Study Group. From this, we acquired the data on 1,487 patients with first-ever atherothrombotic infarction (ATI) or lacunar infarction (LI) with a satisfactory functional outcome on discharge.Results Patients with HL were significantly younger (65.3±11.0 vs 68.4±10.9, p<0.0001) and showed a higher frequency of concomitant hypertension (70.9% vs 61.0%, p=0.0002), diabetes mellitus (42.2% vs 25.7%, p<0.0001) or both (31.7% vs 16.4%, p<0.0001) compared to those without HL. The ratio of ATI to LI and the frequency of prior ischemic heart disease (IHD) did not differ between the 2 groups. Among 467 patients with HL, 52.7% did not receive treatment on admission.Conclusion ATI or LI patients with HL had an earlier age of onset and higher frequency of other lifestyle-related diseases, and this probably includes many with metabolic syndrome, whereas the frequency of IHD was not different between these 2 groups.
- 社団法人 日本内科学会の論文
- 2005-12-01
著者
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Matsumoto Masayasu
Department Of Clinical Neuroscience And Therapeutics Hiroshima University Graduate School Of Biomedi
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KOBAYASHI Shotai
Department of Internal Medicine III, Shimane Medical University
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NOMURA Eiichi
Department of Neurology, Tsuchiya General Hospital of Akane Medical Corporation
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Nomura Eiichi
Department Of Neurology Suiseikai Kajikawa Hospital
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Nomura Eiichi
Department Of Materials Science And Engineering The Graduate School At Nagatsuta Tokyo Institute Of
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KOHRIYAMA Tatsuo
Department of Clinical Neuroscience and Therapeutics, Hiroshima University
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Kobayashi Shotai
Department Of Neurology Hematology And Rheumatology Shimane University School Of Medicine
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Kobayashi Shotai
Department Neurology Hematology & Rheumatology Shimane University School Of Medicine
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Kohriyama Tatsuo
Department Of Clinical Neuroscience And Therapeutics Hiroshima University Graduate School Of Biomedi
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Matsumoto Masayasu
Department Of Clinical Neuroscience And Therapeutics Hiroshima University Graduate School Of Biomedi
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Matsumoto Masayasu
Department Of Clinical Neuroscience And Therapeutics Graduate School Of Biomedical Science Hiroshima University
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Matsumoto Masayasu
Department of Clinical Neuroscience and Therapeutics Division of Integrated Medical Science, Graduate School of Biomedical Sciences, Hiroshima University
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