Evaluation of In Vivo Mutagenicity by 2,4-Diaminotoluene and 2,6-Diaminotoluene in Liver of F344 gpt delta Transgenic Rat Dosed for 28 Days : A Collaborative Study of the gpt delta Transgenic Rat Mutation Assay

スポンサーリンク

概要

• 論文の詳細を見る
• Japanese Environmental Mutagen Societyの論文
• 2012-02-20

著者

• MASUMURA Kenichi

  Division of Genetics and Mutagenesis, National Institute of Health Sciences

• Masumura Kenichi

  Division Of Genetics And Mutagenesis National Institute Of Health Sciences

• Nohmi Takehiko

  Division Of Genetics And Mutagenesis National Institute Of Health Sciences

• Nakajima Madoka

  Biosafety Research Center Foods Drugs And Pesticides

• Sui Hajime

  Division Of Genetic Toxicology Hatano Research Institute Food And Drug Safety Center

• Hayashi Hiroyuki

  Research Planning & Management R&d Planning & Management Dept. Meiji Seika Pharma Co. Lt

• Akahori Ayaka

  Biosafety Research Center Foods Drugs And Pesticides

• OHTA Ryo

  Division of Genetic Toxicology, Hatano Research Institute, Food and Drug Safety Center

• SHIRAGIKU Toshiyuki

  Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd.

• SUZUKI Kenichiro

  Biosafety Research Center, Foods, Drugs and Pesticides

• HAYASHI Hiroyuki

  Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd.

• Shiragiku Toshiyuki

  Tokushima Research Institute Otsuka Pharmaceutical Co. Ltd.

• Nakajima Madoka

  Biosafety Res. Center Foods Drugs And Pesticides (bsrc)

• Ohta Ryo

  Division Of Genetic Toxicology Hatano Research Institute Food And Drug Safety Center

• Suzuki Kenichiro

  Biosafety Research Center Foods Drugs And Pesticides

関連論文

• Spontaneous and Induced gpt and Spi^- Mutant Frequencies in gpt delta Transgenic Rodents
• Spontaneous Mutagenesis in Rodents : Spontaneous Gene Mutations Identified by Neutral Reporter Genes in gpt Delta Transgenic Mice and Rats
• In vivo mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromate
• In vivo mutagenicity and oxidative DNA damage in the livers of gpt delta mice treated with flumequine(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting)
• In Vivo Mutagenesis Caused by Diesel Exhaust in the Testis of gpt delta Transgenic Mice
• In vivo Approaches to Study Mechanism of Action of Genotoxic Carcinogens
• Enhancing effects of carbon tetrachloride on in vivo mutagenicity in the liver of mice fed 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)
• Effects of co-treatment of dextran sulfate sodium and MeIQx on genotoxicity and possible carcinogenicity in the colon of p53-deficient mice
• Application of Genetically Engineered Bacteria Carrying Human Cytochrome P450 to Toxicological Studies
• New Method of Specimen Preparation as Cell Suspension for a Micronucleus Test
• INTERLABORATORY VALIDATION STUDY OF THE SKIN^2 DERMAL MODEL AND MTT CYTOTOXICITY ASSAY KITS
• Chemopreventive Effects of Nobiletin against Genotoxicity Induced by 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in the Lung of gpt delta Transgenic Mice
• Development of Tester Strains Deficient in Nth/Nei DNA Glycosylases to Selectively Detect the Mutagenicity of Oxidized DNA Pyrimidines
• Development of a Bacterial Hyper-sensitive Tester Strain for Specific Detection of the Genotoxicity of Polycyclic Aromatic Hydrocarbons
• Deletion and single nucleotide substitution at G:C in the kidney of gpt delta transgenic mice after ferric nitrilotriacetate treatment
• Detection of DNA adduct using ^32P-postlabeling method(WORKSHOP 4 : NEW TECHNOLOGY AND EVALUATIONS OF IN VIVO TOXICITY STUDIES)
• International Symposium on Genotoxic and Carcinogenic Thresholds
• Mutation Spectra in Cisplatin- and Transplatin-treated GDL1 Cells Clarified the Different Mode of Action of These Compounds in Mammalian Cells
• Oxidative DNA damage and reporter gene mutation in the livers of gpt delta rats given non-genotoxic hepatocarcinogens with cytochrome P450-inducible potency
• EFFECTS OF 7, 8-BENZOFLAVONE AND SKF 525-A ON THE ENZYME-MEDIATED MUTAGENICITY OF PHENYLENEDIAMINES
• DIFFERENTIAL MUTAGENICITIES OF TRIAMINO BENZENES AGAINST SALMONELLA TYPHIMURIUM TA 98 IN THE PRESENCE OF S9 FRACTIONS FROM POLYCHLORINATED BIPHENYLS-, PHENOBARBITAL- OR 3-METHYLCHOLANTHRENE-PRETREATED RATS, HAMSTERS AND MICE
• B-34 Age-associated historical data of the hematology and blood biochemistry in F344 rats and B6C3F_1 mice
• Improvement and Evaluation of High Throughput Fluctuation Ames Test Using 384-well Plate with Salmonella typhimurium TA100 and TA98
• Possible Mechanisms of Practical Thresholds for Genotoxicity
• Zero Spin Sound in Antiferromagnetic Metals: Case of Two-Dimensional $t$–$t'$ Hubbard Model
• Tissue Sample Preparation for In Vivo Rodent Alkaline Comet Assay
• Evaluation of In Vivo Mutagenicity by 2,4-Diaminotoluene and 2,6-Diaminotoluene in Liver of F344 gpt delta Transgenic Rat Dosed for 28 Days : A Collaborative Study of the gpt delta Transgenic Rat Mutation Assay
• Evaluation of the in vivo Mutagenicity of Nickel Subsulfide in the Lung of F344 gpt delta Transgenic Rats Exposed by Intratracheal Instillation : A Collaborative Study for the gpt delta Transgenic Rat Mutation Assay
• Embryonic Lethality in Mice Lacking Mismatch-Specific Thymine DNA Glycosylase Is Partially Prevented by DOPS, a Precursor of Noradrenaline
• Evaluation of the Genotoxicity of Aristolochic Acid in the Kidney and Liver of F344 gpt delta Transgenic Rat Using a 28-Day Repeated-dose Protocol : A Collaborative Study of the gpt delta Transgenic Rat Mutation Assay
• Differences in micronucleus induction in peripheral blood reticulocytes of mice exposed to N-ethyl-N-nitrosourea at light and dark dosing times
• Modulatory Effects of Capsaicin on N-diethylnitrosamine (DEN)-induced Mutagenesis in Salmonella typhimurium YG7108 and DEN-induced Hepatocarcinogenesis in gpt Delta Transgenic Rats
• Gastric mucosal changes induced by polyethylene glycol 400 administered by gavage in rats
• Endocrine Mechanisms Responsible for Different Follicular Development During the Estrous Cycle in Hatano High- and Low-avoidance Rats
• Male Hatano High-Avoidance Rats Show High Avoidance and High Anxiety-Like Behaviors as Compared with Male Low-Avoidance Rats
• Male Hatano High-Avoidance Rats Show High Avoidance and High Anxiety-Like Behaviors as Compared with Male Low-Avoidance Rats
• 2nd International Symposium on Genotoxic and Carcinogenic Thresholds
• in vivo Approaches to Identify Mutations and in vitro Research to Reveal Underlying Mechanisms of Genotoxic Thresholds
• Molecular mechanisms underlying ochratoxin A-induced genotoxicity : global gene expression analysis suggests induction of DNA double-strand breaks and cell cycle progression
• Expression and Activity of Human DNA Polymerase η in Escherichia coli

もっと見る 閉じる

スポンサーリンク