Analysis of Gene Expression in a Human-derived Glial Cell Line Exposed to 2.45 GHz Continuous Radiofrequency Electromagnetic Fields
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概要
- 論文の詳細を見る
The increasing use of mobile phones has aroused public concern regarding the potential health risks of radiofrequency (RF) fields. We investigated the effects of exposure to RF fields (2.45 GHz, continuous wave) at specific absorption rate (SAR) of 1, 5, and 10 W/kg for 1, 4, and 24 h on gene expression in a normal human glial cell line, SVGp12, using DNA microarray. Microarray analysis revealed 23 assigned gene spots and 5 non-assigned gene spots as prospective altered gene spots. Twenty-two genes out of the 23 assigned gene spots were further analyzed by reverse transcription-polymerase chain reaction to validate the results of microarray, and no significant alterations in gene expression were observed. Under the experimental conditions used in this study, we found no evidence that exposure to RF fields affected gene expression in SVGp12 cells.
- Journal of Radiation Research 編集委員会の論文
- 2011-03-16
著者
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SUZUKI Yukihisa
Department of Electrical Engineering, Graduate School of Engineering, Tokyo Metropolitan University
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TAKI Masao
Department of Electrical Engineering, Graduate School of Engineering, Tokyo Metropolitan University
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Miyakoshi Junji
Dep. Of Radiological Life Sciences Div. Of Medical Life Sciences Graduate School Of Health Sciences
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Miyakoshi Junji
Department Of Radiation Genetics Faculty Of Medicine Kyoto University
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Miyakoshi Junji
Department Radiation Genetics Graduate School Of Medicine Kyoto University
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Miyakoshi Junji
Faculty Of Medicine Hirosaki University
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SAKURAI Tomonori
Laboratory of Applied Radio Engineering for Humanosphere, Research Institute for Sustainable Humanos
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KIYOKAWA Tomoko
Department of Radiological Life Sciences, Division of Medical Life Sciences, Graduate School of Heal
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NARITA Eijiro
Laboratory of Applied Radio Engineering for Humanosphere, Research Institute for Sustainable Humanos
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MIYAKOSHI Junji
Laboratory of Applied Radio Engineering for Humanosphere, Research Institute for Sustainable Humanos
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Sakurai Tomonori
Laboratory Of Applied Radio Engineering For Humanosphere Research Institute For Sustainable Humanosp
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Taki Masao
Department Of Electrical Engineering Graduate School Of Engineering Tokyo Metropolitan University
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Narita Eijiro
Laboratory Of Applied Radio Engineering For Humanosphere Research Institute For Sustainable Humanosp
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Kiyokawa Tomoko
Department Of Radiological Life Sciences Division Of Medical Life Sciences Graduate School Of Health
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Suzuki Yukihisa
Department Of Electrical Engineering Graduate School Of Engineering Tokyo Metropolitan University
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Miyakoshi Junji
Laboratory Of Applied Radio Engineering For Humanosphere Research Institute For Sustainable Humanosp
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Taki Masao
Department Of Electric Engineering Faculty Of Engineering Tokyo Met. Univ.
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Suzuki Yukihisa
Department Of Electrical And Electronic Engineering Tokyo Metropolitan University
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Taki Masao
Department of Communications Engineering, Osaka University
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