Identification of Ecl Family Genes That Extend Chronological Lifespan in Fission Yeast

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概要

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• In fission yeast, we identified two genes, named ecl2+ and ecl3+, that are paralogous to ecl1+, which extends the chronological lifespan. Both ecl2+ and ecl3+ extend the chronological lifespan when overexpressed as ecl1+. ecl2+ and ecl3+ encode 84- and 89-amino acid polypeptides respectively that are not annotated in the current database. The Ecl2 protein is localized mainly in the nucleus, as Ecl1. These results suggest that ecl1+, ecl2+, and ecl3+ have overlapping functions in the regulation of chronological lifespan.

• 社団法人 日本農芸化学会の論文
• 2009-04-23

著者

• Mita Satoka

  Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University

• Ohtsuka Hokuto

  Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University

• AIBA Hirofumi

  Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University

• Ogawa Yuki

  Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University

• Mizuno Hiroyuki

  Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University

• Aiba Hirofumi

  Laboratory Of Microbiology Faculty Of Agriculture Nagoya University

• Mizuno Hiroyuki

  Laboratory Of Molecular Microbiology School Of Agriculture Nagoya University

• Ogawa Yuki

  Laboratory Of Molecular Microbiology School Of Agriculture Nagoya University

• Ohtsuka Hokuto

  Laboratory Of Molecular Microbiology School Of Agriculture Nagoya University

• Mita Satoka

  Laboratory Of Molecular Microbiology School Of Agriculture Nagoya University

• Ohtsuka Hokuto

  Laboratory Of Molecular Microbiology Graduate School Of Bioagricultural Sciences Nagoya University

• Aiba Hirofumi

  Laboratory Of Molecular Microbiology Graduate School Of Bioagricultural Sciences Nagoya University

関連論文

• Identification of a Fatty Acyl-CoA Synthetase Gene, lcf2+, Which Affects Viability after Entry into the Stationary Phase in Schizosaccharomyces pombe
• Ecl1, a Regulator of the Chronological Lifespan of Schizosaccharomyces pombe, Is Induced upon Nitrogen Starvation
• Identification of Ecl Family Genes That Extend Chronological Lifespan in Fission Yeast
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