Plasma Fatty Acid Composition, Estimated Desaturase Activities, and Intakes of Energy and Nutrient in Japanese Men with Abdominal Obesity or Metabolic Syndrome
スポンサーリンク
概要
- 論文の詳細を見る
To examine predictive factors for abdominal obesity or metabolic syndrome, we investigated the association of plasma fatty acid composition, estimated desaturase activity, and nutrient intakes, with abdominal obesity or metabolic syndrome in Japanese males. Clinical characteristics, the fatty acid composition of plasma cholesteryl esters, and energy and nutrient intakes were analyzed in 3 groups: metabolic syndrome (MS, n=24), abdominal obesity (OB, n=43), and control (n=27). The estimated desaturase activities were calculated by the ratio of 16:1n-7/16:0, 18:3n-6/18:2n-6, and 20:4n-6/20:3n-6 in plasma cholesteryl esters as surrogates of the measure of the delta 9, delta 6, delta 5 desaturase (D9-16D, D6D and D5D) activities, respectively. Plasma fatty acid composition did not differ significantly between the OB group and the control group. The MS group had higher levels of palmitoleic, oleic, and γ-linolenic acids, but a lower level of linoleic acid than the control. Stronger D6D activity and weaker D5D activity were observed in the OB group. A higher level of D9-16D activity as well as a higher level of D6D activity and a lower level of D5D activity was observed in the MS group. A logistic regression analysis showed that the low D5D activity and high D9-16D activity were predictive of the development of abdominal obesity from controls (odds ratio=0.39, p<0.05) and metabolic syndrome from abdominal obesity (odds ratio=2.44, p<0.05), respectively. In the multiple linear regression analysis, D5D activity positively correlated with the intake of eicosapentaenoic acid (EPA). In conclusion, the estimated D5D activity was a predictive factor for abdominal obesity and the estimated D9-16D activity was a predictive factor for developing metabolic syndrome from abdominal obesity in Japanese male subjects. Dietary intake of EPA would play an important role in preventing abdominal obesity and the development of metabolic syndrome.
- 財団法人 学会誌刊行センターの論文
- 2009-10-01
著者
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OKITA Misako
Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural Univer
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Okita Misako
Dep. Of Food Sci. And Nutrition Nara Women's Univ.
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Okita Misako
Department Of Food Science And Nutrition Nara Women's University
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KAWASHIMA Aiko
Department of Food Science and Nutrition, Nara Women's University
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SUGAWARA Shiori
Department of Food Science and Nutrition, Nara Women's University
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AKAHANE Takemi
Nara Health Promotion Center
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FUKUI Kennichi
Nara Health Promotion Center
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HASHIUCHI Maiko
Nara Health Promotion Center
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KATAOKA Chieko
Nara Health Promotion Center
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TSUKAMOTO Ikuyo
Department of Food Science and Nutrition, Nara Women's University
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Tsukamoto Ikuyo
Dep. Of Food Sci. And Nutrition Nara Women's Univ.
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Sugawara Shiori
Dep. Of Food Sci. And Nutrition Nara Women's Univ.
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Kawashima Aiko
Department Of Food Science And Nutrition Nara Women's University
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Sugawara Shiori
Department Of Food Science And Nutrition Nara Women's University
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Tsukamoto Ikuyo
Department Of Food Science And Nutrition Nara Women's University
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