Does Obesity Attenuate the Effect of Metabolic Syndrome on Chronic Kidney Disease in Patients With Coronary Artery Disease? Report From China Heart Survey
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概要
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Background: The present study explored the relationship between metabolic syndrome (MetS) and chronic kidney disease (CKD) in patients with coronary artery disease (CAD) in China. Methods and Results: The prevalence of MetS and CKD were determined in 3,465 participants with CAD from the China Heart Survey, from June 1st to August 31st 2005. The relationship between MetS and CKD was analyzed. The prevalence of MetS and CKD was 53.0% and 21.1%, respectively. Patients with MetS had a higher prevalence of CKD than those without MetS. All traits of MetS except central obesity were statistically significantly associated with CKD. The multivariate-adjusted odds ratio (OR) of CKD in participants with and without MetS was 1.27 (95% confidence interval (CI) 1.07-1.51). In the multivariate-adjusted model, patients with 3 MetS components, excluding central obesity, had a higher OR for CKD (OR 2.17, 95%CI 1.21-3.88). Conclusions: MetS is a significantly higher risk factor for CKD in patients with CAD. Central obesity might attenuate the effect of MetS on CKD in patients with CKD, regardless of the number of MetS components.
- 2010-02-25
著者
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Hu Dayi
中華人民共和国
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Wang Fang
Department of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology
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Hu Dayi
Heart-lung-blood Vessel Center Of Tongji University Institute Of Heart-lung-blood Vessel Disease Of
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Hu Dayi
Department Of Cardiology People's Hospital Peking University
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Hu Dayi
Department Of Cardiology Beijing Red Cross Chao Yang Hospital Capital University Of Medical Sciences
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Wang Fang
Department Of Electronics Engineering And Institute Of Electronics National Chiao Tung University
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Wang Fang
Department Of Preventive Medicine Medical College Tongji University
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Chen Fang
Department Of Cardiology Beijing Anzhen Hospital Capital Medical University
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Chen Fang
Department Of Preventive Medicine Medical College Tongji University
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Yu Jinming
Institute Of Clinical Epidemiology School Of Public Health Fudan University
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LIU Hao
Institute of Clinical Epidemiology, School of Public Health, Fudan University
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WANG Jinsong
Department of Preventive Medicine, Medical College, Tongji University
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CHEN Shengbao
Department of Preventive Medicine, Medical College, Tongji University
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Liu Hao
Institute Of Clinical Epidemiology School Of Public Health Fudan University
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Liu Hao
Department Of Histology And Embryology Tianjin Medical University
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Wang Jinsong
Department Of Preventive Medicine Medical College Tongji University
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Chen Shengbao
Department Of Preventive Medicine Medical College Tongji University
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Wang Fang
Department Of Chemistry Box 8204 North Carolina State University
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Yu Jinming
Clinical Research Institute School Of Public Health Fudan University
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Hu Dayi
The College Of Medicine Tongji University
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