A Spontaneous Ovarian Immature Teratoma in a Juvenile Rat
スポンサーリンク
概要
- 論文の詳細を見る
A spontaneous ovarian immature teratoma characterized by the presence of tissue derivatives of endoderm, mesoderm and ectoderm was investigated histopathologically in a 6-week-old juvenile Crj:CD(SD)IGS rat. The various kinds of tissue components observed in this teratoma were mainly mature elements derived from three embryonic germ layers, such as nervous tissue, skin, pancreas, salivary gland, gastrointestinal tract, respiratory tracts, striated and smooth muscle, bone with bone marrow, cartilaginous tissue and adipose tissue. Remarkable features were that this teratoma contained immature tissues intermingled with mature tissues, which typically took the form of primitive neuroepithelial rosettes and tubules and islands of immature cartilage, showing evidence of malignancy. A small yolk sac carcinoma-like focus was also observed. Neither invasion nor distant metastases were found in the other organs and tissues. This is the first report of an ovarian immature teratoma in a rat.
- 日本毒性病理学会の論文
- 2004-09-30
著者
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YOSHIZAWA Katsuhiko
Department of Toxicologic Pathology, Toxicology Research Laboratories, Fujisawa Pharmaceutical Co.,
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OISHI Yuji
Department of Toxicologic Pathology, Toxicology Research Laboratories, Fujisawa Pharmaceutical Co.,
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TSUBOTA Kenjiro
Department of Toxicologic Pathology, Toxicology Research Laboratories, Fujisawa Pharmaceutical Co.,
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Oishi Yuji
アステラス製薬安全性研究所
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Oishi Yuji
Central Research Institute Of Electric Power Industry
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Oishi Yuji
Department Of Toxicologic Pathology Toxicology Research Laboratories Fujisawa Pharmaceutical Co. Ltd
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義澤 克彦
Department Of Pathology Ii Kansai Medical University
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Yoshizawa Katsuhiko
Toxicologic Pathology Drug Safety Research Labs. Astellas Pharma Inc.
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Yoshizawa Katsuhiko
Department Of Pathology Ii Kansai Medical University
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Yoshizawa Katsuhiko
Department Of Toxicologic Pathology Toxicology Research Laboratories Fujisawa Pharmaceutical Co. Ltd
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Matsumoto Masahiro
Department Of Clinical Physiology Tokyo Metropolitan Institute Of Gerontology
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FUJIHIRA Shiro
Department of Pathology, Toxicology Research Laboratories, Fujisawa Pharmaceutical Co. Ltd.
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Tsubota Kenjiro
Toxicologic Pathology Drug Safety Research Laboratories Astellas Pharma Inc.
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Ohishi Yuji
Department Of Obstetrics And Gynecology Kawasaki Medical School
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Matsumoto Masahiro
Drug Safety Research Laboratories, Astellas Pharma Inc.
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OKAZAKI Yoshimasa
Toxicologic Pathology, Drug Safety Research Labs., Astellas Pharma Inc.
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OKAZAKI Yoshimasa
Department of Toxicologic Pathology, Toxicology Research Laboratories, Fujisawa Pharmaceutical Co.,
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NAKATSUJI Shunji
Department of Toxicologic Pathology, Toxicology Research Laboratories, Fujisawa Pharmaceutical Co.,
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Matsumoto Masahiro
Toxicologic Pathology Drug Safety Research Laboratories Astellas Pharma Inc.
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Ohishi Yuji
Toxicology Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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Fujihira Shiro
Toxicologic Pathology Drug Safety Research Labs. Astellas Pharma Inc.
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Tsubota Kenjiro
Department Of Toxicologic Pathology Fujisawa Pharmaceutical Co. Ltd.
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Okazaki Yoshimasa
Toxicologic Pathology Drug Safety Research Labs. Astellas Pharma Inc.
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Nakatsuji Shunji
Department Of Pathology Toxicologic Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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Tsubota Kenjiro
Department of Chemistry, Faculty of Engineering, Gifu University
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MATSUMOTO Masahiro
Department of Applied Chemistry, Graduate School of Engineering, Osaka University
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