A Case of Pancreatic Nesidioblastosis with Aberrant Islet Cell Proliferation in a Beagle
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概要
- 論文の詳細を見る
A 20-month-old female beagle showed a pancreatic nesidioblastosis with a curious proliferation of islet hormone-positive cells. These cells were characterized by a tubular or columnar pattern, occasionally with a rosette-like structure. Immunohistochemistry revealed that they were positive to insulin and chromogranin A and weakly-positive to glucagon and somatostatin in the cytoplasm, but negative for cytokeratin. PCNA- positive cells were also scattered among these proliferating cells. The present case appears to be a specific type of nesidioblastosis accompanied by a proliferation of previously unidentified islet-cells in a beagle.
- 日本毒性病理学会の論文
- 2004-03-30
著者
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Enomoto Makoto
Biosafety Research Center Foods Drugs And Pesticides (an-pyo Center)
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IWATA Hijiri
Department of Pathology, Biosafety Research Center, Foods, Drugs and Pesticides
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ENOMOTO Makoto
Department of Pathology, St. Marrianna University School of Medicine
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OHIRA Toko
Department of Pathology, Biosafety Research Center, Foods, Drugs and Pesticides
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ISHIZAKI Mayumi
Department of Pathology, Biosafety Research Center, Foods, Drugs and Pesticides
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YAMAKAWA Seiki
Department of Pathology, Biosafety Research Center, Foods, Drugs and Pesticides
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IMAI Kiyoshi
Department of Pathology, Biosafety Research Center, Foods, Drugs and Pesticides
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Iwata Hijiri
Biosafety Research Center Foods Drugs And Pesticides (an-pyo Center)
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Iwata Hijiri
Department Of Pathology Biosafety Research Center
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Enomoto Makoto
Department Of Cell Processing Institute Of Medical Science University Of Tokyo
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Yamakawa Seiki
Department Of Pathology Biosafety Research Center Foods Drugs And Pesticides
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Ohira Toko
Department Of Pathology Biosafety Research Center Foods Drugs And Pesticides
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Ishizaki Mayumi
Biosafety Research Center Food Drugs And Pesticides
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Imai Kiyoshi
Biosafety Research Center Foods Drugs And Pesticides (an-pyo Center)
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Imai Kiyoshi
Department Of Animal Sciences Nihon University
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Iwata Hijiri
Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center)
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