A Spontaneously Occurring Renal Tubule Carcinoma in a Mouse
スポンサーリンク
概要
- 論文の詳細を見る
Spontaneous occurrence of renal tubule carcinoma in mice is known to be rare. The following features of this tumor are recognized as areas of hemorrhage and massive necrosis and many show atypical cells and numerous mitotic figures. The present renal tubule carcinoma developed in an untreated B6C3F1 male mouse at the age of 109 weeks. The tumor mass occupied nearly the entire renal cortex and invasion of normal renal tissue was observed. The tumor had solid cell nests, a gland-like structure, definite neovascularization and capsular invasion. The tumor cells had clear eosinophilic cytoplasm, a brush border structure and high proliferative activity. Although tumors derived from the proximal tubule reportedly show basophilic cytoplasm, the tumor cells in this mouse had clear eosinophilic cytoplasm. Consequently, the animal was diagnosed as having an unusual renal tubule carcinoma (classification: solid type).
- 日本毒性病理学会の論文
- 2007-12-25
著者
-
IWATA Hijiri
Biosafety Research Center
-
Imai Kiyoshi
Biosafety Research Center Foods Drugs And Pesticides
-
Hosoi Masayo
Biosafety Research Center Food Drugs And Pesticides
-
Iwata Hijiri
Biosafety Research Center Foods Drugs And Pesticides (an-pyo Center)
-
Shiga Atsushi
Biosafety Research Center Foods Drugs And Pesticides (an-pyo Center)
-
Yamashita Ryo
Biosafety Research Center Food Drugs And Pesticides
-
Ishizaki Mayumi
Biosafety Research Center Food Drugs And Pesticides
-
Imai Kiyoshi
Biosafety Research Center Foods Drugs And Pesticides (an-pyo Center)
-
Ueda Yoshihide
Biosafety Research Center, Foods, Drugs and Pesticides (BSRC)
-
Miyajima Rumiko
Biosafety Research Center, Foods, Drugs and Pesticides (BSRC)
-
Hasegawa Kazushige
Biosafety Research Center, Foods, Drugs and Pesticides (BSRC)
-
YASUI Yuzo
Biosafety Research Center, Foods Drugs and Pesticides (An-Pyo Center)
-
NAGAI Kayoko
Biosafety Research Center, Foods Drugs and Pesticides (An-Pyo Center)
-
KIHARA Tohru
Biosafety Research Center, Foods Drugs and Pesticides (An-Pyo Center)
-
Hasegawa Kazushige
Biosafety Research Center Foods Drugs And Pesticides (an-pyo Center)
-
Yasui Yuzo
Biosafety Research Center Foods Drugs And Pesticides (an-pyo Center)
-
Nagai Kayoko
Biosafety Research Center Foods Drugs And Pesticides (an-pyo Center)
-
Kihara Tohru
Biosafety Research Center Foods Drugs And Pesticides (an-pyo Center)
-
Miyajima Rumiko
Biosafety Research Center Foods Drugs And Pesticides (an-pyo Center)
-
Ueda Yoshihide
Biosafety Research Center Foods Drugs And Pesticides (bsrc)
-
Iwata Hijiri
Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center)
関連論文
- Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats
- Toxicologic/carcinogenic Effects of Endocrine Disrupting Chemicals on the Female Genital Organs of Rodents
- ANALYSIS OF BACKGROUND PATHOLOGICAL LESIONS SEEN IN LONG-TERM TOXICITY TESTS (1). THE COMBINED HISTOPATHOLOGICAL CHANGES OBSERVED IN RATS OR MICE
- (+)-[^3H] Isradipine and [^3H] Glyburide Bindings to Heart and Lung Membranes From Rats With Monocrotaline-Induced Pulmonary Hypertension
- Analysis of Ras Gene Mutations in Main Spontaneously-occurring Non-epithelial Tumors of B6C3F_1 Mouse
- Two Cases of Rare Hepatocellular Nodular Lesion Caused by Circulatory Disturbance in Rat Livers
- A Case of Pancreatic Nesidioblastosis with Aberrant Islet Cell Proliferation in a Beagle
- ACUTE TOXICITY OF PIERISIN-1, A CYTOTOXIC PROTEIN FROM PIERIS RAPAE, IN MOUSE AND RAT
- Study on the Pathogenesis of Foreign Body Granulomatous Inflammation in the Livers of Sprague-Dawley Rats
- Spontaneous Pituitary Carcinoma of the Pars Intermedia in a B6C3F1 Mouse
- A Spontaneously Occurring Renal Tubule Carcinoma in a Mouse
- Analysis of organ weight data in Beagle dog
- Gastric mucosal changes induced by polyethylene glycol 400 administered by gavage in rats
- Neuropathological Evaluation of Acrylamide- and 3,3'-Iminodipropionitrile-Induced Neurotoxicity in a Rat 28-Day Oral Toxicity Study-Collaborative Project for Standardization of Test Procedures and Evaluation of Neurotoxicity
- Cartilage-forming Tumors at Multiple Sites in Two B6C3F_1 Mice
- Study on the Pathogenesis of Foreign Body Granulomatous Inflammation in the Livers of Sprague-Dawley Rats
- Analysis of Ras Gene Mutations in Main Spontaneously-occurring Non-epithelial Tumors of B6C3F1 Mouse.
- Vimentin/Cytokeratin Coexpression Foci in a Well-Differentiated Canine Hepatocellular Carcinoma.