PEPTIDOME Database and Identification of New Bioactive Peptides

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概要

• 論文の詳細を見る
• 2007-03-01

著者

• Kodama H

  Department Of Chemistry Faculty Of Science And Engineering Saga University

• Kodama Hiroaki

  Dept. Biore. Chem. Fac. Horti. Chiba Univ.

• Kuwahara H

  Department Of Chemistry Faculty Of Science And Engineering Saga University

• Minamino Naoto

  National Cardiovascular Center Research Institute

• Minamino Naoto

  Department Of Pharmacology National Cardiovascular Center Research Institute

• Minamino Naoto

  National Cardiovascular Center Res. Inst. Osaka Jpn

• Osaki Tsukasa

  National Cardiovascular Center Res. Inst. Osaka Jpn

• Osaki Tsukasa

  Department Of Pharmacology National Cardiovascular Center Research Institute

• KUWAHARA Hiromiki

  National Cardiovascular Center Research Institute

• KATAFUCHI Takeshi

  National Cardiovascular Center Research Institute

• Takao Toshifumi

  Institute for Protein Research, Osaka University

• Takao Toshifumi

  Institute For Protein Research Osaka University

• SASAKI Kazuki

  National Cardiovascular Center Research Institute

• KIHARA Takahiro

  National Cardiovascular Center Research Institute

• ISOYAMA TANAKA

  National Cardiovascular Center Research Institute

• ISOYAMA Masaharu

  Protein Research Foundation

• Minamino N

  Department Of Pharmacology National Cardiovascular Center Research Institute

• Isoyama M

  Protein Research Foundation

• Kihara Takahiro

  Department Of Molecular Pharmacology National Cerebral And Cardiovascular Center Research Institute

• Katafuchi Takeshi

  Department Of Molecular Pharmacology National Cerebral And Cardiovascular Center Research Institute

関連論文

• Trans-Bilayer Ion Conduction by Proline Containing Cyclic Hexapeptides and Effects of Amino Acid Substitutions on Ion Conducting Properties
• OJ-105 Diversity of Molecular Forms of BNP in Heart Failure : Difference of Molecular Form of BNP in Atrial and Ventricular Overload(OJ18,Heart Failure (Laboratory/Biomarkers) (M),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japa
• Structure-Activity Relationship of Model Peptides Capable of Ion Channel Formation
• OJ-047 Proangiotensin-12 : a New Member of Peptide for the Renin-angiotensin (RA) System(Hypertension, basic-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Modifications of Hydrophobic Value and Hydrophobic Moment Value of Cationic Model Peptides for Conversion of Peptide-Membrane Interactions
• Antiadhesive Sites Present in the Fibronectin TypeIII-Like Repeats of Human Plasma Fibronectin
• Enhancement of Ion Channel Formation by Electrostatic Interaction Incorporated in Dimeric Helical Peptide
• Synthesis and Ion Conductance of Cervinin Peptides
• Antiadhesive Sites Present in the Fibronectin Type III-Like Repeats of Human Plasma Fibronectin(Molecular and Cell Biology)
• Comparison Study of Ion Channel Activities of Homo-Dimerized and Hetero-Dimerized Amphiphilic Helical Model Peptides
• Effect of Ring Size Alteration for Ion Channel Activities of Cyclic Peptides
• Solid-phase Synthesis of Tyrosine-containing Cyclic Peptides
• Ion-Channel Properties of Cyclic Hexapeptide cyclo(Pro-Xxx-Yyy)_2
• Synthesis and Ion-Channel Activity of Assembled Aib-Model Peptides
• ORIGIN OF THE RENIN-ANGIOTENSIN SYSTEM IN VERTEBRATES
• Effect of α,α-Dialkyl Amino Acids on the Protease Resistance of Peptides(Organic Chemistry)
• The Position of Aib Residues Defines the Antimicrobial Activity of Aib-Containing Peptides
• Synthesis and Properties of Transmembrane Domains of Uncoupling Protein, UCP-2
• Side Chain Effect on Ion Channel Characters of Aib Rich Peptides
• Pore-Forming Properties and Ion Selectivity of Amphiphilic Helical Aib-containing Model Peptides
• Interaction of Alanine-based Peptides with Fluoresceins and Their Fluorescence Quenching Behavior
• Interaction and Orientation of an α-Aminoisobutyric Acid-and Tryptophan-Containing Short Helical Peptide Pore-Former in Phospholipid Vesicles, as Revealed by Fluorescence Spectroscopy^1
• Structural Change in Elastin Model Peptides upon Interaction with Biologically Important Metal Ions
• シクロプロパンアミノ酸の合成と立体制約因子としての生理活性ペプチドへの導入
• COSUPPRESSION OF THE ω-3 FATTY ACID DESATURASES
• Characterization of the Arabidopsis rfc3 mutant that forms aberrant lateral roots in a sugar-concentration dep endent manner
• POSSIBLE INVOLVEMENT OF PROTEIN PHOSPHORYLATION IN THE WOUND RESPONSIVE EXPRESSION OF ARBIDOPSIS PLASTID ω-3 FATTY ACID DESATURASE GENE
• ACCUMULATION OF ER ω-3 FATTY ACID DESATURASE IS ENHANCED AT LOW TEMPERATURE IN WHEAT ROOT TIP
• A Ti-plasmid-convertible λ Phage Vector System Harboring the Hygromycin B Phosphotransferase Gene
• Developmental Regulation of Genes for Microsome and Plastid ω-3 Fatty Acid Desaturases in Wheat (Triticum aestivum L.)
• EFFECT OF GROWTH TEMPERATURE ON DEVELOPMENTALLY REGULATED EXPRESSION OF THE MICROSOME ω-3 DESATURASE GENE IN WHEAT ROOT
• MOLECULAR MECHANISM OF WOUND-RESPONSIVE EXPRESSIONS OF THE ARABIDOPSIS FAD7 GENE
• WOUND-INDUCED EXPRESSION OF THE FAD7 GENE IS REGULATED BY TWO DIFFERENT WOUND-RESPONSIVE REGIONS OF ITS PROMOTER SEQUENCE
• cDNA Cloning of a Wounding-Inducible Gene Encoding a Plastid ω-3 Fatty Acid Desaturase from Tobacco
• NORTHERN BLOT ANALYSIS OF THE TRANSGENIC TOBACCO PLANTS SHOWING A SILENCING OF THE PLASTID ω-3 FATTY ACID DESATURASE GENES
• STRUCTURE AND EXPRESSION OF A RICE GENE ENCODING THE MICROSOME ω-3 FATTY ACID DESATURASE
• CHANGES IN LINOLENIC ACID LEVEL AND EXPRESSION OF A GENE FOR ER ω-3 FATTY ACID DESATURASE DURING LEAF AND ROOT CELL MATURATION IN WHEAT
• CLONING OF A WOUND-INDUCIBLE GENE ENCODING A PLASTID ω-3 FATTY ACID DESATURASE FROM TOBACCO
• Wounding drastically modulates the spatial expression pattern of the Arabidopsis chloroplast ω-3 fatty acid desaturase gene(FAD7)promoter in transgenic tobacco plants
• A Ti-PLASMID-CONVERTIBLE λ PHAGE VECTORSYSTEM TO SIMPLIFY GENETIC COMPLEMENTATION IN MAP-BASED CLONINGMETHOD
• OVER AND ANTISENSE EXPRESSION OF AMICROSOMAL ω-3 FATTY ACID DESATURASE GENE IN TRANSGENIC TOBACCO
• Analysis of the promoter region of achloroplast ω-3 fatty add desaturase gene(FAD7) from Arabidopsisthaliana
• EFFECTS OF AGING AND LIGHT ON LINOLEICACID DESATURATION AND EXPRESSION OF A GENE FOR PLASTID ω-3 FATTYACID DESATURASE IN WHEAT LEAF TISSUES
• FATTY ACID DESATURATION DURING CHILLINGACCLIMATION IS INVOLVED IN CONFERRING LOW TEMPERATURE TOLERANCE
• Structural Profiles for Coacervation of Elastin-derived Polypeptides
• Reversible Affinity Labeling of Opioid Receptors via Disulfide Bonding: Discriminative Labeling of μ and δ Subtypes by Chemically Activated Thiol-Containing Enkephalin Analogs
• Synthesis of Protected Peptides Containing Phosphoserine with Oxime Resin
• Oligomerization Process of the Hemolytic Lectin CEL-III Purified From a Sea Cucumber, Cucumaria echinata
• Effects of Chemical Modification of Carboxyl Groups in the Hemolytic Lectin CEL-III on Its Hemolytic and Carbohydrate-Binding Activities
• Carbohydrate-Dependent Hemolytic Activity of the Conjugate Composed of a C-Type Lectin, CEL-I, and an Amphiphilic α-Helical Peptide, 4_3-βAla_2
• Characterization of the Interaction of Hemolytic lection CEL-III from the Marine Invertebrate, Cucumaria echinata, with Artificial Lipid Membranes : Involvement of Neutral Sphingoglycolopids in the Pore-Forming Process
• Preparation of A Ca^〈2+〉-Dependent Lectin-Basic Amphiphilic Peptide Conjugate, and Its Interaction with Biomembrane
• Chemical Modification of the Hemolytic Lectin CEL-III by Succinic Anhydride : Involvement of Amino Groups in the Oligomerization Process
• Structural and Functional Role of Prosequence Part in Melittin Precursor
• Synthesis and Properties of TN III Peptide Analogs Derived from Type III Repeat of Tenascin C
• Programmed Cell Death of Malignant Cell Types through Integrin Signal Activation
• CONSTRUCTION OF A Ti-PLASMIDCONVERTIBLE λ PHOSPHOTRANSFERASE GENE HYGROMYCIN B PHOSPHOTRANSF ERASE GENE
• PEPTIDOME Database and Identification of New Bioactive Peptides
• Peptidome Database and Identification of New Endogenous/Bioactive Peptides
• The Receptor-Gα Fusion Protein as a Tool for Ligand Screening : a Model Study Using a Nociceptin Receptor-Gα_ Fusion Protein
• Efficient Data Acquisition System for Peptidome Database
• Peptidome Project : Its Purpose And Methods
• Conformational Studies of Cyclo(Pro-Leu-Aib)_2 by ^1H Nuclear Magnetic Resonance Spectroscopy and Circular Dichroism^1
• Synthesis and Solution Conformations of Cyclo(Pro-Leu-Gly)_2 and Cyclo(Pro-Leu-Gly)_4
• Synthesis and Conformational Studies of Cyclic Peptides Containing the C-terminal Tripeptide Sequence of Oxytocin
• Elastin-derived Peptides : Structure, Functions and Mechanisms
• Synthesis and Biological Activity of Synthetic Peptide MMK-1 Analogs
• Synthesis and Biological Activity of Non-Formyl Chemotactic Peptide Analogs as a Tool for Neutrophil Formyl Peptide Receptor Interaction
• Synthesis of FPR-Derived Transmembrane Peptides Containing Photoaffinity Amino Acid
• Superoxide Production in Human Neutrophils Is Enhanced by Treatment with Transmembrane Peptides Derived from Human Formyl Peptide Receptor
• Characterization of Active Sequence in the Integrin-Activating Peptide (TNIII) and Its Cell Surface Mediators
• Signal Transduction of Chemotactic Non-Formyl Peptide and Selective for Formyl Peptide Receptor
• Synthesis of Transmembrane Peptides Derived from Human Formyl Peptide Receptor and Influence on Biological Activities of Human Neutrophils
• L-5, 5-Difluoronorleucine as an Oxidation-Resistant Methionine Mimic : Facile Synthesis and its Application on Chemotactic Peptide, fMLP
• Synthesis and Biological Activity of Urease-related Peptides Generated from Helicobacter Pylori
• Interacions of Amphiphilic Aib-containing Helical Peptides with Phospholipid Membrane
• Synthesis and Secondary Structures of Aib Peptides Containing Tryptophan Residues
• Structure-Function Relationship of Model Aib-Containing Peptides as Ion Transfer Intermembrane Templates^1
• TRIENOIC FATTY ACIDS : A KEY FACTOR FOR PLANT ADAPTABILITY TO GROWTH AT HITH TEMPERATURE
• Ion Channel Formation and Sequence Dependence of Aib-containing Peptides
• Activation of Betal Integrins by the FNIII14 Analogous Peptide Induces Programmed Cell Death of Malignant Cell Types
• Photoaffinity Labeling of Formylpeptide Receptors by fMLP Analogs
• Synthesis and Neutrophil Activation of fMLP Analogs Containing Conformationally Constrained Tic Residues
• Effects of Peptide Dimerization on Pore Formation : Antiparallel Disulfide-Dimerized Magainin 2 Analog
• Chemical Synthesis of Phosphorylated Peptides of The Carboxy-Terminal Domain of Human p53 by A Segment Condensation Method
• Synthesis and Biological Activity of Dimeric Chemotactic Peptide Antagonist
• Insight into Methionine Side-Chain Recognition by the FPR Utilizing Sulfur Mimetics
• Synthesis and Biological Activity of Alamethicin Analogs Enhanced by Electrostatic Interaction
• Synthesis and Priming Activities of Cyclic Peptides, Hymenamides
• Facile Synthesis of (S)-5,5-Difluoronorleucine and Its Incorporation in Biologically Active Peptides as an Methionine Mimetic
• ACTIVATION OF HUMAN NEUTROPHILS BY fMLP ANALOGS CONTAINING 2,3-CYCLOPROPANE AMINO ACID
• Dimeric Chemotactic Peptides Discriminate between Chemotaxis and Superoxide Production of Human Neutrophils
• Solid-phase Synthesis and Chain-length Dependence of The Secondary Structure of α-Helical Model Peptides Containing Aib Residues
• Breeding of a Low Pyruvate-Producing Sake Yeast by Isolation of a Mutant Resistant to Ethyl α-Transcyanocinnamate, an Inhibitor of Mitochondrial Pyruvate Transport
• A Tetrameric Enkephalin Analog for the Putative Multivalent Interaction with Opioid Receptors
• Contribution of hydrophobic side-chain in cyclic tetrapeptide forming ion channel
• Structural modification of 2-aminoisobutylic acid containing peptides toward an acquiring of antimicrobial activities against pathogenic bacteria
• Synthesis of 3-Substituted 2,3-Dehydroprolines: Oxidative Decarboxylation of Ethy Hydrogen Acetoamidomalonate Derivatives
• Design and Synthesis of Highly Specific and Selective Enkephalin Analog Containing S-Npys-Cysteine for δ Opioid Receptors
• Protease-Immobilized Microreactor for Rapid and Site-Specific Affinity Tag Cleavage

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