Anti-Diabetic Effect of Alkaline-Reduced Water on OLETF Rats
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概要
- 論文の詳細を見る
Alkalin-reduced water (ARW) is known to exert several anti-cancer effects, as well as to scavenge reactive oxygen species (ROS) and reduce blood-glucose levels. This study was performed in order to determine the effects of ARW on the control of spontaneous diabetes in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.We assigned 16 male OLETF rats (4 wk) to two groups: an experimental group, which was given ARW, and a control group, which received laboratory tap water. From week 6 to 32, the body weight, lipid composition, and glucose levels in the blood of the rats were measured. The glucose levels of both groups tended to increase. However, the ARW group’s glucose levels were significantly lower than those of the control group after 12 weeks (p<0.05). The total cholesterol and triglyceride levels in the ARW group were found to be significantly lower than those of the control group during the experimental period.These results suggest that ARW spurred the growth of OLETF rats during the growth stage, and that long-term ingestion of ARW resulted in a reduction in the levels of glucose, triglycerides, and total cholesterol in the blood.
- 社団法人 日本農芸化学会の論文
- 2006-01-23
著者
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KIM Hyun
Department of Internal Medicine, Chonnam National University Hospital
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LEE Kyu
Department of Environmental Medical Biology, Wonju College of Medicine, Yonsei University
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JIN Dan
Department of Immunology and Pathogenic Biology, College of Basic Medicine, Yanbian University
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LIM Soo
Department of Internal Medicine, Seoul National University College of Medicine
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Park Seung
Department Of Medicine Samsung Medical Center Sungkyunkwan University School Of Medicine
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Lee Kyu
Deparment Of Obstetrics & Gynecology College Of Medicine Pusan National University
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Ryu Sung
Department Of Biochemistry Wonju College Of Medicine Yonsei University
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Yang Eun
Department Of Biomedical Laboratory Science School Of Medicine Eulji University
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Lim Soo
Department Of Biomedical Laboratory Science And Institute Of Health Science College Of Health Scienc
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Park Seung
Department Of Anatomy Wonkwang University School Of Medicine
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Jin Dan
Department Of Immunology And Pathogenic Biology College Of Basic Medicine Yanbian University
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Jin Dan
Department Of Microbiology Wonju College Of Medicine Yonsei University
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Yang Eun
Department Of Biomedical Laboratory Science And Institute Of Health Science College Of Health Scienc
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Kim Hyun
Department Of Agricultural Biotechnology And Center For Agricultural Biomaterials Seoul National Uni
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RYANG Yong
Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Scien
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CHUNG Choon
Department of Internal Medicine, Wonju College of Medicine, Yonsei University
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Ryang Yong
Department Of Biomedical Laboratory Science And Institute Of Health Science College Of Health Scienc
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Chung Choon
Department Of Internal Medicine Wonju College Of Medicine Yonsei University
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Kim Hyun
Department Of Biochemistry Wonju College Of Medicine Yonsei University
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Lee Kyu
Department Of Parasitology And Institutes For Basic Medical Science Wonju College Of Medicine Yonsei
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Park Seung
Department Of Parasitology And Institutes For Basic Medical Science Wonju College Of Medicine Yonsei
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Kim Hyun
Department Of Agricultural Bio-resources National Academy Of Agricultural Science Rural Development
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Park Seung
Department Of Anatomy College Of Medicine Konkuk University
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Kim Hyun
Department of Advanced Material Engineering, Daejeon University, Daejeon 300-716, Republic of Korea
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