Hepatoprotective Activity of the Constituents in Swertia pseudochinensis(Pharmacognosy)

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概要

• 論文の詳細を見る

• A new xanthone derivative was isolated together with other 13 known constituents from a Chinese natural medicine, Swertia pseudochinensis HARA. Their structures were determined based on the spectral and chemical evidences. Furthermore, respective hexane, ethyl acetate, 1-BuOH, MeOH and water extracts of S. pseudochinensis, and purified compounds were respectively evaluated for their hepatoprotective activities against hepatocyte injury induced by CCl_4. All the extracts and isolated compounds exhibited significant hepatoprotective activities at a dose showing no hepatoxicity.

• 公益社団法人日本薬学会の論文
• 2005-03-01

著者

• Nohara Toshihiro

  Faculty of Pharmaceutical Sciences, Sojo University

• IKEDA Tsuyoshi

  Faculty of Pharmaceutical Sciences, Kumamoto University

• Nohara Toshihiro

  Faculty Of Pharmaceutical Sciences Kumamoto University

• Li J‐c

  Kumamoto Univ. Kumamoto Jpn

• Ikeda Tsuyoshi

  Faculty Of Medical And Pharmaceutical Science Kumamoto University

• Nohara Toshihiro

  Faculty Of Medical And Pharmaceutical Science Kumamoto University

• LI Jian

  Faculty of Pharmaceutical Sciences, Kumamoto University

• FENG Li

  Hebei Province Pharmaceutical Examining Institute

• SUN Bao

  Hebei Province Pharmaceutical Examining Institute

• Feng L

  Nippon Medical School Tokyo Jpn

• Li Jian-chen

  Faculty Of Pharmaceutical Sciences Kumamoto University

• Li Jian-chen

  Faculty Of Pharmaceutical Sciences Kumamoto Univeristy

• Sun Bao-Hui

  Hebei Province Pharmaceutical Examining Institute

• Ikeda Tsuyoshi

  Faculty of Medical and Pharmaceutical Sciences, Kumamoto University

• Nohara Toshihiro

  Faculty of Medical and Pharmaceutical Scieces, Sojo University

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