Eleven New 2-Pyrones from a Fungi Imperfecti, Trichurus terrophilus, Found in a Screening Study Guided by Immunomodulatory Activity
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概要
- 論文の詳細を見る
In a screening study on immunomodulatory fungal constituents, eleven new 2-pyrones tentatively named TT-1 (1), and TT-2-11 (2-11) have been isolated from a Fungi Imperfecti, Trichurus terrophilus, and designated rasfonin (1), and trichurusin B-K (2-11), respectively. Compounds 1-4 exhibited considerably high immunosuppressive activities, and compounds 8-11 have shown moderate ones. The structure-activity relationships of these constituents have also been discussed.
- 社団法人日本薬学会の論文
- 2005-08-01
著者
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Ishibashi Masami
Graduate School of Pharmaceutical Sciences, Chiba University
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Akiyama Kohki
Graduate School Of Life And Environmental Sciences Osaka Prefecture Univ.
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Akiyama Kohki
Graduate School Of Pharmaceutical Sciences Chiba University
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Akiyama Kohki
Graduate School Of Agriculture And Biological Sciences Osaka Prefecture University
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FUJIMOTO Haruhiro
Graduate School of Pharmaceutical Sciences, Chiba University
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OKAMOTO Yoshie
Graduate School of Pharmaceutical Sciences, Chiba University
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SONE Eriko
Graduate School of Pharmaceutical Sciences, Chiba University
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MAEDA Satomi
Graduate School of Pharmaceutical Sciences, Chiba University
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Ishibashi Masami
Graduate School Of Pharmaceutical Sciences Chiba Univ.
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Ishibashi Masami
Graduate School Of Pharmaceutical Sciences Chiba University
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Sone Eriko
Graduate School Of Pharmaceutical Sciences Chiba University
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Maeda Satomi
Graduate School Of Pharmaceutical Sciences Chiba University
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Okamoto Yoshie
Graduate School Of Pharmaceutical Sciences Chiba University
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Fujimoto Haruhiro
Fac. Of Pharmaceutical Sciences Teikyo Heisei Univ.
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