Constituents of Pongamia pinnata Isolated in a Screening for Activity to Overcome Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Resistance
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概要
- 論文の詳細を見る
In a search for natural products with activity to overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistance, we performed the bioassay-guided fractionation of a semi mangrove, Pongamia pinnata, collected from Bangladesh, and isolated a new compound, (2S)-(2″,3″:7,8)-furanoflavanone (1), along with six known flavonoids (2—7). Two of the compounds significantly overcame TRAIL-resistance in human gastric adenocarcinoma (AGS) cell lines.
- 公益社団法人 日本薬学会の論文
著者
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Toume Kazufumi
Graduate School of Pharmaceutical Sciences, Chiba University
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Ahmed Firoj
Graduate School of Pharmaceutical Sciences, Chiba University
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Sadhu Samir
Pharmacy Discipline, Life Science School, Khulna University
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Ishibashi Masami
Graduate School of Pharmaceutical Sciences, Chiba University
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Toume Kazufumi
Graduate School Of Pharmaceutical Sciences Chiba University
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OHTSUKI Takashi
Graduate School of Pharmaceutical Sciences, Chiba University
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Sadhu Samir
Pharmacy Discipline Life Sci. School Khulna Univ.
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Arai Midori
Graduate School of Pharmaceutical Sciences, Chiba University
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Ohtsuki Takashi
Graduate School Of Pharmaceutical Sciences Chiba Univ.
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Ishibashi Masami
Graduate School Of Pharmaceutical Sciences Chiba Univ.
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Arai Midori
Graduate School Of Pharmaceutical Sciences Chiba Univ.
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Minakawa Tomohiro
Graduate School of Pharmaceutical Sciences, Chiba University
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Ahmed Firoj
Graduate School Of Pharmaceutical Sciences Chiba University
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