Association Between Plasma Lipoprotein(a) Concentration and Restenosis After Stent Implantation
スポンサーリンク
概要
- 論文の詳細を見る
Background The plasma concentration of lipoprotein (a) [Lp(a)] is associated with atherosclerotic and thrombotic vascular diseases. The aim of the present study was to evaluate the association between plasma Lp(a) concentration and in-stent restenosis. Methods and Results One hundred and 9 patients with successful elective coronary stent implantation underwent follow-up angiography at 24±6 weeks. Restenosis after stent implantation occurred in 38 patients. Univariate analysis showed that the reference diameter of the lesion was smaller in the restenosis group (2.93±0.29mm) than in the no-restenosis group (3.21±0.43mm) (p<0.05). The lesion was longer in the restenosis group (14.2±5.3mm) than in the no-restenosis group (11.6±4.9mm) (p<0.05). Plasma Lp(a) concentrations in the restenosis group (30.5±23.9mg/dl) were higher than in the no-restenosis group (16.9±11.1mg/dl) (p<0.01). Other lipid concentrations were similar in both groups. Among the plasma Lp(a) concentrations, the rate of restenosis (71.4%) in the high Lp(a) group (>40mg/dl) (n=14) was greater compared with the other groups: 33.3% in the intermediate Lp(a) group (10-40mg/dl) (n=54), and 24.4% in the low Lp(a) group (<10mg/dl) (n=41) (p<0.01). The late loss (0.57±0.53mm) in the low Lp(a) group was significantly less than the other groups: 0.88±0.47mm in the intermediate Lp(a) group, and 1.08±0.56mm in the high Lp(a) group (p<0.05). In a multivariate regression model, plasma Lp(a) concentration remained significant as an independent predictor of restenosis in patients undergoing stent implantation (p=0.020 odds ratio (OR) 1.37 95% conficence interval (CI) 1.050-1.793), although the reference diameter (p=0.025 OR 0.23 95%CI 0.061-0.830) and lesion length (p=0.021 OR 1.12 95%CI 1.017-1.232) were related to stent restenosis. Conclusions Plasma Lp(a) concentration is an independent predictor of stent restenosis.
- 社団法人日本循環器学会の論文
- 2005-05-20
著者
-
MIYAI Nobuyuki
Department of Cardiology, Kouseikai Takeda Hospital
-
Taniguchi Takuya
Department of Cardiology, National Cardiovascular Center
-
Sugihara H
Department Of Cardiology Matsushita Memorial Hosipital
-
Taniguchi Takuya
Department Of Cardiology Matsushita Memorial Hospital
-
Kawasaki Tatsuya
Department of Cardiology, Matsushita Memorial Hospital, Japan
-
Kamitani Tadaaki
Department of Cardiology, Matsushita Memorial Hospital, Japan
-
Sugihara Hiroki
Department of Cardiology, Matsushita Memorial Hospital
-
Kamitani Tadaaki
Department Of Cardiology Matsushita Memorial Hosipital
-
Kamide Takashi
Department Of Cardiovascular Medicine Kyoto Prefectural University Of Medicine
-
Taniguchi Takuya
Department Of Applied Chemistry Faculty Of Engineering Okayama University Of Science
-
Kawasaki Shingo
Department of Cardiology, Matsushita Memorial Hospital
-
Sugihara Hiroki
松下電器健康保険組合松下記念病院 循環器科
-
SHIRAISHI Hirokazu
the Kyoto Prefectural Yosanoumi Hospital
-
Kawasaki Tatsuya
Department Of Cardiology Matsushita Memorial Hosipital
-
Kamide Takashi
Department Of Cardiology Matsushita Memorial Hospital
-
Kawasaki Shingo
Department Of Cardiology Matsushita Memorial Hospital
-
Sugihara Hiroki
Department Of Cardiology Kyoto Prefectural University Of Medicine
-
Miyai Nobuyuki
Department Of Cardiology Kouseikai Takeda Hospital
-
Miyai Nobuyuki
Department Of Cardiology Matsushita Memorial Hospital
-
Shiraishi Hirokazu
京都府立与謝の海病院
-
Hirasaki Satoshi
Department Of Cardioology Matsushita Memorial Hospital
-
Kusaba Tetsuro
Division Of Cardiology And Nephrology Department Of Medicine Kyoto Prefectural University Of Medicin
-
Sugihara Hiroki
The 2nd. Dept. Of Int. Med. Kyoto Pref. Univ. Of Med.
関連論文
- PJ-409 Identification of Clinical Characteristics Favorably Treated with Non-Stent Strategy for Sirolimus-Eluting Stent Restenosis : Insights from J-CYPHER Registry(PJ069,Coronary Revascularization, PCI (Restenosis/Others) 1 (IHD),Poster Session (Japanese
- Erythropoietin in Patients With Acute Coronary Syndrome and Its Cardioprotective Action After Percutaneous Coronary Intervention
- PJ-409 Identification of Clinical Characteristics Favorably Treated with Non-Stent Strategy for Sirolimus-Eluting Stent Restenosis : Insights from J-CYPHER Registry(PJ069,Coronary Revascularization, PCI (Restenosis/Others) 1 (IHD),Poster Session (Japanese
- OJ-218 Risk Factors for Recurrent Restenosis of Post-Sirolimus-Eluting Stent Restenosis : Insights From j-CYPHER Registry(Restenosis basic / clinical(02)(IHD),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soci
- Could Myocardial Staining with Computed Tomography Just after Direct PTCA for Acute Myocardial Infarction Predict the Size of Infarction? (X-ray/CT/MRI/DSA 8 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-039 Postprandial Left Ventricular Performance Change in Patients with Acute Myocardial Infarction(Nuclear Cardiology 3 (I) : PJ7)(Poster Session (Japanese))
- PJ-452 The Presence of Previous Cerebral Infarction in Vertebrobasilar System may Exacerbate Ventilatory Oscillations during Exercise in Patients with Heart Failure(PJ076,Exercise Test/Cardiac Rehabilitation 1 (H),Poster Session (Japanese),The 73rd Annual
- PE-507 Slower Periodic VO_2 Oscillations during Exercise Indicate Poorer Prognosis of Patients with Heart Failure(PE085,Exercise Test/Cardiac Rehabilitation (H),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Societ
- PJ-869 Is the Extent of Exercise VO2 Oscillations Related to the Severity of Heart Failure?(Exercise test / Cardiac rehabilitation(08)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-868 Exercise May Exert as a Trigger to Magnify the Preexisting Oscillation at Rest(Exercise test / Cardiac rehabilitation(08)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-101 Incidence and Clinical Characteristics of Exercise VO2 Oscillations: A Single-Center Experience from 4792 Consecutive Exercise Tests(Exercise test/Cardiac rehabilitation(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japa
- PJ-100 Exercise Ventilatory Oscillations Disappear during Intense Exercise, Which is Temporally Coincident with the Disappearance of Lag-Time between VE and ETCO2(Exercise test/Cardiac rehabilitation(05)(H),Poster Session(Japanese),The 72nd Annual Scienti
- OE-178 Slower Periodic VO2 Oscillations during Exercise Indicate Worse Clinical Status of Patients with Heart Failure(Exercise test/Cardiac rehabilitation(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Soc
- PE-517 The Optimal Revascularization Strategy in Elderly Women with Coronary Artery Disease : Sirolimus-eluting Stent vs. Off-pump Coronary Artery Bypass Surgery(PE087,Cardiovascular Surgery/CABG (IHD),Poster Session (English),The 73rd Annual Scientific M
- PJ-693 Are There Gender Differences in Pre-hospital Delay Time Interval for Acute Myocardial Infarction?(Emergency care / CPR(04)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Spatial Illusion Revealing "Shrinking" Stent
- PJ-232 Postconditioning and Early ST-Segment Resolution in Patients with Acute Myocardial Infarction and Its Cardioprotective Action after Mechanical Reperfusion Therapy(PJ039,Cardiac Function (Clinical) 2 (M),Poster Session (Japanese),The 73rd Annual Sci
- PJ-340 The Relationship between Progression of Coronary Artery Plaques and Plaque Composition : Virtual Histology Intravascular Ultrasound Analysis(Intravascular endoscopy/Intravascular ultrasound(06)(I),Poster Session(Japanese),The 72nd Annual Scientific
- PE-507 Long term outcome of contrast-induced nephropathy after coronary angiography in diabetes patient with chronic kidney disease(Coronary revascularization, PCI(15)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circula
- Septal q Wave as a Marker of Septal Ischemia in Hypertrophic Cardiomyopathy
- Electrocardiographic Score as a Predictor of Mortality After Subarachnoid Hemorrhage
- OJ-162 Active Smoking is an Independent Risk Factor of Metabolic Syndrome in Acute Myocardial Infarction Patients via Alteration of Lipid Profile(Smoking(H),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Societ
- PJ-743 A Comparison of Re-restenosis Results and Treatment Technique for Restenosis Lesion : Sirolimus-eluting Stent Versus Bare Metal Stent(Coronary revascularization, PCI-20, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-431 Coronary Artery Plaque Assessment Using Volcano Therapeutics' Virtual Histology TM IVUS and Temperature Guide Wire(Atherosclerosis, clinical-12, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-667 Intervention for Smaller Coronary Arteries Using 2.25-mm Bare-metal Stents(Coronary revascularization, PCI-21 (IHD) PJ112,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-498 Assessment of cardiomyopathy with transient ballooning of the mid-base of the left ventricle. A new form of Takotsubo cardiomyopathy(Cardiomyopathy, basic/clinical-6 (M) PJ84,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting
- PJ-423 Restenosis Following Sirolimus-eluting Stent Implantation for Ostial Lesions(Restenosis, basic/clinical-5 (IHD) PJ71,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-287 Erythropoietin, And Endothelial Progenitor Cells in Patients with Acute Coronary Syndrome and Its Cardioprotective Action after Ischemia-reperfusion Injury(Acute coronary syndrome, basic/clinical-6 (IHD) PJ49,Poster Session (Japanese),The 70th Anni
- PJ-114 Assessment of the Latent Congestive Heart Failure in Patients with Arterial Fibrillation Using I-123 BMIPP Myocardial Images(Nuclear cardiology-8 (I) PJ19,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circ
- OJ-170 Assessment of Lipid Pool of Coronary Artery Plague. -Gray Scale IVUS vs. Virtual Histology IVUS(Echo/Doppler-4 (I) OJ29,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-136 Coronary Artery Plaque Assessment Using Volcano Therapeutics Virtual Histology IVUS and a Temperature Guidewire(Atherosclerosis, clinical-4 (H) OJ23,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circula
- OJ-099 Limitation of Sirolimus Eluting Stent for Recurrent In-stent Restenosis(Coronary revascularization, PCI-5 (IHD) OJ17,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Assessment of Coronary Microcirculation Disturbance in Patients with Coronary Ectasia with ATP Loading Tc-99m-Tetrofosmin Myocardial SPECT
- Effectiveness of Transcatheter Mechanical Thrombus Aspiration in Patients with Acute Coronary Syndrome
- Expression and Function of CD36 on the Human Myocardium
- Increasing myocardial ^I-BMIPP uptake in non-ischemic area in a patient with acute myocardial ischemia
- SHAPE CHANGE OF ERYTHROCYTES BY CALMODULIN INHIBITORS
- Convenient Synthesis of (+)-Decarestrictine L
- Association Between Plasma Lipoprotein(a) Concentration and Restenosis After Stent Implantation
- Mechanical Evaluation of Paradoxical Wall Motion after Coronary Artery Bypass Grafting by Using MR Tagging Technique(X-ray/CT/MRI/DSA 10 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Clinical Significance of Brain Natriuretic Peptide and QRS Duration as a Predictor for Cardiac Events in Patients with Heart Failure(Heart Failure, Clinical 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-422 Enhanced Vagal Modulations and Exercise-Induced Subendocardial Ischemia in Patients With Hypertrophic Cardiomyopathy(Cardiomyopathy, Clinical 5 (M) : PJ71)(Poster Session (Japanese))
- PJ-271 Assessment of paradoxical wall motion after open heart surgery by using MR tagging technique(X-ray/CT/MRI/DSA5 (I) : PJ46)(Poster Session (Japanese))
- PJ-190 Exercise Test With Heart Rate Variability Analysis may Contribute to the Diagnosis of Ischemic Areas in Patients With Angina Pectoris(Exercise Test/Cardiac Rehabilitation 2 (IHD) : PJ32)(Poster Session (Japanese))
- OJ-307 Anemia is an Independent Predictor for Cardiac Events in Patients With Congestive Heart Failure(Heart Failure, Clinical 9 (M) : OJ37)(Oral Presentation (Japanese))
- Surgical Removal of Intra-Aortic Balloon Cathetet With Fractured Nitinol Central Lumen : A Case Report
- Assessment of ampulla (Takotsubo) cardiomyopathy with coronary angiography, two-dimensional echocardiography and ^Tc-tetrofosmin myocardial single photon emission computed tomography
- A patient with type I CD36 deficiency whose myocardium accumulated ^123 I-BMIPP after 4 years
- Reverse redistribution of Tc-99m-tetrofosmin in patients with acute myocardial infarction
- Prediction of functional recovery and prognosis in patients with acute myocardial infarction by ^I-BMIPP and ^TI myocardial single photon emission computed tomography : A multicenter trial
- Effect of exercise-induced activation of sympathetic nerve activity on clearance of ^I-MIBG from the myocardium
- Administration of Mesenchymal Stem Cells-Derived Endothelial Cells Aggravated Luminal Narrowing after Arterial Injury in Mice(Restenosis after Angioplasty, Basic/Clinical 2 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-300 Novel Hydroxyl Radicals Scavenger, Inhibits Neointimal Hyperplasia after Arterial Wire Injury in Mice(Restenosis after Angioplasty, Basic/Clinical 2 (IHD) : OJ36)(Oral Presentation (Japanese))
- Idiopathic Long QT Syndrome With Early Afterdepolarization Induced by Epinephrine : A Case Report
- Subepicardial Aneurysm Associated With Ventricular Septal Perforation Showing a Normal Coronary Angiogram
- A Case of Cardiomyopathy Induced by Premature Ventricular Complexes
- Two Cases of Polymorphic Ventricular Tachycardia Induced by the Administration of Verapamil against Paroxysmal Supraverntricular Tachycardia
- Characteristics of coronary artery in patients with acute myocardial infarction associated with sleep apnea syndrome
- Very Low Frequency Power of Heart Rate Variability is a Powerful Predictor of Clinical Prognosis in Patients With Congestive Heart Failure
- Heart Rate Turbulence and Clinical Prognosis in Hypertrophic Cardiomyopathy and Myocardial Infarction
- Usefulness of Washout Rate of Tc-99m-Tetrofosmin for Evaluation of Severity of Aortic Regurgitation
- Mechanical Evaluation of Left Ventricular Contractility by Meridional Strain Using MR Tagging Technique
- Analysis of Short-Term Fluctuation in Sinus Cycle Length after Premature Ventricular Beats in Patients with Hypertrophic Cardiomyopathy
- Autonomic Nervous Alterations Associated with Exercise in Patients with Hypertrophic Cardiomyopathy
- Very Low Frequency Is a Powerful Predictor of Clinical Prognosisin Patients with Congestive Heart Failure
- Cardioinhibitory Reflex Is Provoked by Exercise-Induced Myocardial Ischemia of the Inferior Wall
- Mechanism of Discocyte-stomatocyte Transformation of Human Red Cells : Alteration of Molecular Organizations in Lipid Bilayer and Cytoskeletal Network
- ORGAN BLOOD FLOW AND ITS DISTRIBUTION IN MITRAL STENOSIS AT REST AND DURING EXERCISE : Valvular Heart Disease : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Novel Application of the Hemostatic Device TOMETA KUN^
- Usefulness of washout rate of Tc-99m-tetrofosmin for evaluation of severity of heart failure
- Long-term follow-up of myocardial perfusion and metabolic images in patients with of dilated phase hypertrophic cardiomyopathy
- Uncommon and dynamic changes detected by ^I-15-(p-iodophenyl)-3-R, S-methylpentadecanoic acid myocardial single photon emission computed tomography in a stunned myocardium induced by coronary microvascular spasm
- Assessment of Takotsubo (ampulla) cardiomyopathy using ^Tc-tetrofosmin myocardial SPECT : Comparison with acute coronary syndrome
- ACE Inhibitor Improves Impaired Myocardial Energy Metabolism and Diastolic Function as Well as Left Ventricular Hypertrophy inHypertensive Patients
- Isolated Left Ventricular Noncompaction Was not a Very Rare Disorder in an Adult Population
- Reverse redistribution of Tc-99m-tetrofosmin in exercise myocardial SPECT in patients with hypertrophic cardiomyopathy
- PJ-806 Quantitative Evaluation of Left Ventricular Torsional Motion Using MR Tagging Technique(MRI/MRA-3 (I) PJ142,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-339 Vagal Enhancement Due to Subendocardial Ischemia as a Cause of Abnormal Blood Pressure Response in Hypertrophic Cardiomyopathy(Cardiomyopathy, basic/clinical-5 (M) PJ57,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the
- Serum Leptin Levels in Healthy Adolescents: Effects of Gender and Growth
- Causes of hearing impairment evaluated by the upper limit of hearing among Chinese people in an urban area
- A Cohort Study on Raynaud's Phenomenon in Workers Exposed to Low Level Hand-Arm Vibration
- The Standardized Nordic Questionnaire Applied to Workers Exposed to Hand-Arm Vibration
- Early and delayed Tc-99m-tetrofosmin myocardial SPECT in patients with left bundle branch block
- SYSTOLIC AND DIASTOLIC FUNCTIONS OF RIGHT VENTRICLE IN HYPERTROPHIC CARDIOMYOPATHY : Myocardial Disease (II) : FREE COMMUNICATIONS (II) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Assessment of Takotsubo cardiomyopathy (transient left ventricular apical ballooning) using ^Tc-tetrofosmin, ^I-BMIPP, ^I-MIBG and ^Tc-PYP myocardial SPECT
- Effects of diltiazem on myocardial perfusion abnormalities during exercise in patients with hypertrophic cardiomyopathy
- PJ-529 Earlobe Crease as a Marker of Coronary Artery Diseases(PJ089,Atherosclerosis (Clinical/Pathophysiology) 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-808 Exercise F-18 Deoxyglucose Positron Emission Tomography for Detection of Myocardial Ischemia in Hypertrophic Cardiomyopathy(Cardiomyopathy, basic / clinical(07)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulat
- PJ-099 Vagal Enhancement as Evidence of Residual Ischemia After Inferior Myocardial Infarction(Exercise test/Cardiac rehabilitation(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-119 Absent Septal Q Wave due to Subendocardial Ischemia in Patients with Hypertrophic Cardiomyopathy(Exercise test/Cardiac rehabilitation-6, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-231 Prognostic Value of B-type Natriuretic Peptide in Patients with Heart Failure : Relation to Left Ventricular Hypertrophy(Heart failure, clinical-07, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Gated Single-Photon Emission Computed Tomography Detects Subendocardial Ischemia in Hypertrophic Cardiomyopathy
- USEFULNESS OF DIPYRIDAMOLE LOADING MYOCARDIAL SCINTIGRAPHY BY CONSECUTIVE DOUBLE DOSE Tl-201 : Radio Isotope : 46th Annual Scientific Meeting, Japanese Circulation Society
- OJ-190 Chronotropic Incompetence and Autonomic Dysfunction in Patients without Structural Heart Disease(OJ32,Exercise Test/Cardiac Rehabilitation (H),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Dynamic changes in cardiac fatty acid metabolism in the stunned human myocardium
- A Dynamic Change be ^I-15-(p-Iodophenyl)-3-R, S-Methyl pentadecanoic Acid Myocardial Single Photon Emission Computed Tomography in a 55-Year-Old Woman
- A Novel Method for Synthesis of Cellooligosaccharide Derivatives by Using Enzyme Catalyst
- Holter Monitoring and Cardiovascular Events in Patients with Hypertrophic Cardiomyopathy
- Cardiac Lipoma
- Usefulness of the Percentage of Plasma Lymphocytes as a Prognostic Marker in Patients With Congestive Heart Failure: Comparison With Brain Natriuretic Peptide:Comparison With Brain Natriuretic Peptide